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The Clinical and Ethical Practice of Neuromodulation – Deep Brain Stimulation and Beyond
Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
The Noonday Demon
WITH A NEW EPILOGUE BY THE AUTHOR Like Primo Levi's The Periodic Table, The Noonday Demon digs deep into personal history, as Andrew Solomon narrates, brilliantly and terrifyingly, his own agonising experience of depression. Solomon also portrays the pain of others, in different cultures and societies whose lives have been shattered by depression and uncovers the historical, social, biological, chemical and medical implications of this crippling disease. He takes us through the halls of mental hospitals where some of his subjects have been imprisoned for decades; into the research labs; to the burdened and afflicted poor, rural and urban. He talks to faith healers and voyages around the world in a quest for folk wisdom. He analyses the medications of today as well as reviewing the politics of diagnosis and treatment and, perhaps most significantly, he looks at the vital role of will and love in the process of recovery. **ONE OF THE GUARDIAN'S 100 BEST BOOKS OF THE 21st CENTURY**
Hello I Want to Die Please Fix Me: Depression in the First Person
An engrossing memoir-meets-investigative report that takes a fresh, frank look at how we treat depression. Depression is a havoc-wreaking illness that masquerades as personal failing and hijacks your life. After a major suicide attempt in her early twenties, Anna Mehler Paperny resolved to put her reporter’s skills to use to get to know her enemy, setting off on a journey to understand her condition, the dizzying array of medical treatments on offer, and a medical profession in search of answers. Charting the way depression wrecks so many lives, she maps competing schools of therapy, pharmacology, cutting-edge medicine, the pill-popping pitfalls of long-term treatment, the glaring unknowns...
Brain Stimulation
- A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
Mood Disorders
Written by an outstanding team of internationally recognised experts, this practical textbook is based on the European Certificate in Anxiety and Mood Disorders. It provides a thorough overview of diagnosis and treatment of mood disorders and analyses the most recent developments and scientific evidence. Covers the most important clinical topics in the field, including symptomatology, natural course and diagnosis Treatment strategies are reviewed in the light of all available empirical evidence Outstanding list of international contributors
Understanding Depression
Depression is a major cause of morbidity and a significant public health problem. This book brings together world leaders in research on depression to discuss both classical and innovative ideas for understanding this devastating disorder. It includes cutting edge research from neurobiology, psychology, genetics, and evolutionary biology.
Touch
Described by Aristotle as the most vital of senses, touch contains both the physical and the metaphysical in its ability to express the determination of being. To manifest itself, touch makes a movement outwards, beyond the body, and relies on a specific physical involvement other senses do not require: to touch is already to be active and to activate. This fundamental ontology makes touch the most essential of all senses. This volume of ‘Law and the Senses’ attempts to illuminate and reconsider the complex and interflowing relations and contradictions between the tactful intrusion of the law and the untactful movement of touch. Compelling contributors from arts, literature and social sc...
Ethics in Psychiatry
Ethics in Psychiatry: (1) presents a comprehensive review of ethical issues arising in psychiatric care and research; (2) relates ethical issues to changes and challenges of society; (3) examines the application of general ethics to specific psychiatric problems and relates these to moral implications of psychiatry practice; (4) deals with recently arising ethical problems; (5) contains contributions of leading European ethicists, philosophers, lawyers, historians and psychiatrists; (6) provides a basis for the exploration of culture-bound influences on morals, manners and customs in the light of ethical principles of global validity.
Handbook of Neurotoxicology
N eurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, 1ead, mercury, and the polytypic byproducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins ofbroadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidentalI...
Ethics of Medical Innovation, Experimentation, and Enhancement in Military and Humanitarian Contexts
This book discusses ethical questions surrounding research and innovation in military and humanitarian contexts. It focuses on human enhancement in the military. Recently, the availability of medical enhancement designed to make soldiers more capable of surviving during conflict, as well as enabling them to defeat their enemies, has emerged. Innovation and medical research in military and humanitarian contexts may thus yield positive effects, but simultaneously leads to a number of highly problematic ethical issues. The work contains contributions on medical ethics that take into account the specific roles and obligations of military and humanitarian health care providers and the ethical problems they encounter. They cover different aspects of research and innovation such as vaccine development, medical enhancement, compassionate and experimental drug use, research and application of new technologies such as wearables, “Humanitarian innovation” to cope with scarce resources, Biometrics, big data, etc.The book is of interest and importance to researchers and policy makers involved with human enhancement, medical research, and innovation in military and humanitarian missions.
