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Defining Therapy Goals for Major Molecular Remission in Chronic Myeloid Leukemia: Results of the Randomized CML Study IV
Abstract: Major molecular remission (MMR) is an important therapy goal in chronic myeloid leukemia (CML). So far, MMR is not a failure criterion according to ELN management recommendation leading to uncertainties when to change therapy in CML patients not reaching MMR after 12 months. At monthly landmarks, for different molecular remission status Hazard ratios (HR) were estimated for patients registered to CML study IV who were divided in a learning and a validation sample. The minimum HR for MMR was found at 2.5 years with 0.28 (compared to patients without remission). In the validation sample, a significant advantage for progression-free survival (PFS) for patients in MMR could be detected...
Marine Compounds and Cancer
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Adreßbuch Mannheim
None
Microarray Innovations
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
Prannie Rhatigan's Irish Seaweed Kitchen
Irish seaboard lore, recipes old & new, nutritional information & personal anecdote combine with the faintest hint of nostalgia in this refreshingly original mix of common sense & practical cookery.
ISCN 2009
This publication updates the now classic system of human cytogenetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research (formerly: Cytogenetics and Cell Genetics) since 1963.Revised and finalized by the ISCN Committee and its advisors at a meeting in Vancouver, B.C., in October 2008, the ISCN 2009 updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations.What is new in ISCN 2009? - New idiograms at all band levels have been revised based upon higher-resolution analysis of banded chromosomes- The neopl...
The Urban Revolution
Originally published in 1970, The Urban Revolution marked Henri Lefebvre’s first sustained critique of urban society, a work in which he pioneered the use of semiotic, structuralist, and poststructuralist methodologies in analyzing the development of the urban environment. Although it is widely considered a foundational book in contemporary thinking about the city, The Urban Revolution has never been translated into English—until now. This first English edition, deftly translated by Robert Bononno, makes available to a broad audience Lefebvre’s sophisticated insights into the urban dimensions of modern life.Lefebvre begins with the premise that the total urbanization of society is an i...
Encyclopedia of Molecular Pharmacology
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
