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Mammalian Transient Receptor Potential (TRP) Cation Channels
  • Language: en
  • Pages: 569

Mammalian Transient Receptor Potential (TRP) Cation Channels

  • Type: Book
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  • Published: 2014-06-24
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  • Publisher: Springer

​In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Nanoarchitectonics for Brain Drug Delivery
  • Language: en
  • Pages: 381

Nanoarchitectonics for Brain Drug Delivery

  • Type: Book
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  • Published: 2024-02-22
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  • Publisher: CRC Press

This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...

Reports of the United States Tax Court
  • Language: en
  • Pages: 388

Reports of the United States Tax Court

  • Type: Book
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  • Published: 2006
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  • Publisher: Unknown

None

North Eastern Reporter
  • Language: en
  • Pages: 1184

North Eastern Reporter

  • Type: Book
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  • Published: 1937
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  • Publisher: Unknown

None

Legionella Pneumophila Macrophage Infectivity Potentiator Protein Appendage Domains Modulate Protein Dynamics and Inhibitor Binding
  • Language: en

Legionella Pneumophila Macrophage Infectivity Potentiator Protein Appendage Domains Modulate Protein Dynamics and Inhibitor Binding

  • Type: Book
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  • Published: 2023
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  • Publisher: Unknown

Macrophage infectivity potentiator (MIP) proteins are widespread in human pathogens including Legionella pneumophila, the causative agent of Legionnaires' disease and protozoans such as Trypanosoma cruzi. All MIP proteins contain a FKBP (FK506 binding protein)-like prolyl-cis/trans-isomerase domain that hence presents an attractive drug target. Some MIPs such as the Legionella protein (LpMIP) have additional appendage domains of mostly unknown function. In full-length, homodimeric LpMIP, the N-terminal dimerization domain is linked to the FKBP-like domain via a long, free-standing stalk helix. Combining X-ray crystallography, NMR and EPR spectroscopy and SAXS, we elucidated the importance of...

Indonesia
  • Language: en
  • Pages: 800

Indonesia

  • Type: Book
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  • Published: 1986
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  • Publisher: Unknown

None

Reports of the United States Tax Court, Volume 126, January 1, 2006 to June 30, 2006
  • Language: en
  • Pages: 388

Reports of the United States Tax Court, Volume 126, January 1, 2006 to June 30, 2006

Within each case, a briefing of the original petition with the Docket Number and date of file is stated followed by Opinion, Background, Tax Court Petition, Respondent's Motion, Petitioner's Motion, Amended Petition (if applicable), Discussion includes statuary language and former petitioners' cases, if applicable, and allegations, motions, followed by conclusion. For a list of cases found in this volume, please refer to the Table of Contents that has a listing of Cases