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80 anos da CLT
A ASSOCIAÇÃO BRASILEIRA DE ADVOGADOS TRABALHISTAS: ABRAT, pensando em marcar e comemorar os 80 anos da Consolidação da Legislação Trabalhista: CLT no ano de 2023, idealizou uma obra coletiva e convidou diversos profissionais e juristas que refletissem em diversas perspectivas, tanto jurídica, quanto histórica, filosófica e sociológica. A obra nos olhares de advogados, professores, pesquisadores e magistrados contempla análises e críticas que traduzem, em especial, a preocupação com o desmonte da Legislação trabalhista no ano de 2017 advinda com a Lei n. 13.467, chamada de reforma trabalhista, objeto de inúmeras críticas já que eivada de inconstitucionalidades. Vale a pena a leitura da obra - 80 anos da CLT. Reflexões e críticas - profundamente enriquecedora e construtiva, já que fruto de pesquisas e desabafos dos autores que construíram seus textos dentro de normas de escrita científica.
Historical Seismology
Modern seismology has faced new challenges in the study of earthquakes and their physical characteristics. This volume is dedicated to the use of new approaches and presents a state-of-the-art in historical seismology. Selected historical and recent earthquakes are chosen to document and constrain related seismic parameters using updated methodologies in the macroseismic analysis, field observations of damage distribution and tectonic effects, and modelling of seismic waveforms.
Transgenic Models in Pharmacology
Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Secondary Schizophrenia
Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.
Metabolism in Cancer
This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Environmentally Friendly Coastal Protection
Coast lines have been and still are the central lines of civilization around the world with still increasing pressure from both sides – the hinterland and the sea – with all its foreseeable and unforeseeable impacts by means of nature or mankind. While the response of nature to such impacts is flexible in the way that all morphological changes with all the consequences are tolerated as part of the system, humanity cannot tolerate short-term or long-term changes without being threatened in its physical and economical existence. The objectives of this Advanced Research Workshop (ARW) on Environmentally Friendly Coastal Structures were: - to contribute to the critical assessment of existing...
Medicinal Natural Products
This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Protein Networks and Pathway Analysis
From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "genome-wide" assays in order to understand the essential biology that lies beneath it. In Protein Networks and Pathway Analysis, expert practitioners present a compilation of methods of functional data analysis, often referred to as "systems biology," and its applications in drug discovery, medicine and basic disease research. The volume is divided into three convenient sections, covering the elucidation of protein, compound and gene interactions, analytical tools, including networks, interactome and ontologies, and applications of functional analysis. As a volume in the highly successful Methods in Molecular BiologyTM series, this work provides detailed descriptions and hands-on implementation advice. Authoritative and cutting-edge, Protein Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.
Modeling the Psychopathological Dimensions of Schizophrenia
Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathologica...
