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Total Synthesis of Plakortide E and Biomimetic Synthesis of Plakortone B
In his thesis, Xiaoyu Sun conducts the first total synthesis of all possible stereoisomers of plakortide E and also confirms the absolute configuration of natural plakortide E. Xiaoyu Sun subsequently converts Plakortide E methyl ester to plakortone B in a biomimetic conversion. Construction and functionalization of cyclic peroxides are notoriously difficult due to the very low O-O bond dissociation energy. Plaktoride E is isolated from the Jamaican marine sponge platorits halichondrioides and contains a five-membered peroxide ring, with oxygen atoms linked to tertiary C4 and C6 centers. The methodology used for synthesizing highly substituted cyclic peroxides is novel and useful, and not only extends the field of Pd-catalyzed reactions, but also provides a convenient synthetic approach for the preparation of the 1,2-dioxolanes series. Plakortide E and plakortone B are bioactive, which means that the synthetic studies on them and their analogs are pivotal in drug discovery.
The Struggles of an Ordinary Man - The Turbulent History of China Through a FarmerÕs Eyes from 1900 to 2000 (Volume One)
"The Struggles of an Ordinary Man(Volume one)- The Turbulent History of China Through a Farmer's Eyes from 1900 to 2000 is the true record of one hundred years of modern history in rural areas of the Eastern Shandong Peninsula from the 1900 to 2000, including the end of the Qing Dynasty, the Anti-Japanese War (1938-1945), China's War of Liberation (1945-1949), the development of China after liberation (1950-1957), the Great Leap Forward Movement (1958-1959), the Three-year Disasters (1960-1962), the Socialist Education Movement (1964-1965), the Great Cultural Revolution (1966-1976) and the reform and opening up of China (1978-2000). This work, with the spirit of unvarnished realism and true-life style, illustrates the actual life and inner mind of an ordinary man in rural areas and through his eyes to see the significant changes of China during the past one hundred years. This book restores the true-life stories of the ordinary rural man with a fair view.
Modeling Risk Management in Sustainable Construction
In this edited volume, we present the state-of-the-art views of the perspective of enterprise risk management, to include frameworks and controls in the ERM process with respect to supply chains, constructions, and project, energy, environmental and sustainable development risk management. The bulk of this volume is devoted to presenting a number of modeling approaches that have been (or could be) applied to enterprise risk management in construction.
Learning and Memory
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Reborn as a Hamster for 233 Days
Price will be 5.99 for the first two weeks. Will be increased to 7.99 afterwards. The renowned SI Corporation’s chief designer, Xiao Yu, is young, promising, and brimming with talent. Who would have guessed that the heavens would be jealous of this heroic genius?! After waking up from a car accident, he unexpectedly finds that he is reborn as a hamster! Never mind that he’d turned into a hamster, but the CEO rival he hated the most in his previous life adopted him! Hamster Xiao declared: Hnn, I’m gonna screw up your company! Chairman Yan: The weather is turning cold, it’s time to buy clothes for my hamster and bankrupt SI along the way.
Case Reports in Neurocritical and Neurohospitalist Care, volume III - 2023
This Research Topic aims to collect all the Case Reports submitted to the Neurocritical and Neurohospitalist Care section. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.
Mechcomp2
Composites materials have aroused a great interest over the last few decades. Several applications of fibrous composites, functionally graded materials, laminated composites, nano-structured reinforcements, morphing structures, can be found in many engineering fields, such as aerospace, mechanical, naval and civil engineering. The necessity of lightweight structures, smart and adaptive systems, high-level strength, have led both the academic research and the manufacturing development to a recurring employment of these materials. Many journal papers and technical notes have been published extensively over the last seventy years in international scientific journals of different engineering fie...
Transmigrate to be an Ancient Saint
He had accidentally traveled back to the ancient times and only wanted to be a teacher, but in the end, he had become a Great Saint Master who was admired by many.Shangguan Wan'er: I am the first student of Xiao Wen Sheng ShiZhuge Liang: Don't call me the God of War, my Xiao Wen Sheng is the real God of War.Wu Zetian: I was able to become an ancient female emperor all because of the careful nurturing of Xiao Wen Sheng Shi.Hua Tuo: My medical skills were taught to me by my Saint Xiao Wen.Qin Shi Huang: Master Xiao Wen Sheng is a god-like person. He can create all kinds of impossible miracles!Liu Bang: I am honored, Xiao Wen Sheng is the teacher of my country.Li Shimin: Master Xiao Wen Sheng is the person I admire the most, not one of them.
Intelligent Computing Methodologies
This two-volume set of LNCS 12463 and LNCS 12464 constitutes - in conjunction with the volume LNAI 12465 - the refereed proceedings of the 16th International Conference on Intelligent Computing, ICIC 2020, held in Bari, Italy, in October 2020. The 162 full papers of the three proceedings volumes were carefully reviewed and selected from 457 submissions. The ICIC theme unifies the picture of contemporary intelligent computing techniques as an integral concept that highlights the trends in advanced computational intelligence and bridges theoretical research with applications. The theme for this conference is “Advanced Intelligent Computing Methodologies and Applications.” Papers related to this theme are especially solicited, addressing theories, methodologies, and applications in science and technology.
