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The Gut-Skin Axis: Interaction of Gut Microbiome and Skin Diseases
More and more evidence has demonstrated that gut microbiome plays critical roles in modulating the development of diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The new conception ‘gut-skin axis’ refers to the bidirectional relationship between the gut microbiome and skin health. Several mechanisms, such as intestinal barrier, inflammatory mediators, and metabolites, have been proposed for gut-skin axis. Currently, there have been various studies regarding the presence of the gut-skin axis and its resulting inflammatory effect due to gut microbiome imbalance. In addition, dysbiosis of the skin and gut microbiota is also observed in skin disorders. Therefore, understanding the gut-skin axis, especially in terms of microbiome modulation, is important for the gut and skin health, which may lead to development of novel therapies for skin disease.
China's Human Rights Lawyers
This book offers a unique insight into the role of human rights lawyers in Chinese law and politics. In her extensive account, Eva Pils shows how these practitioners are important as legal advocates for victims of injustice and how bureaucratic systems of control operate to subdue and marginalise them. The book also discusses how human rights lawyers and the social forces they work for and with challenge the system. In conditions where organised political opposition is prohibited, rights lawyers have begun to articulate and coordinate demands for legal and political change. Drawing on hundreds of anonymised conversations, the book analyses in detail human rights lawyers’ legal advocacy in ...
Alcohol-Associated Liver Disease - From Pathogenesis to Treatment
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Ultrasonic Guided Waves
The propagation of ultrasonic guided waves in solids is an important area of scientific inquiry, primarily due to their practical applications for nondestructive characterization of materials, such as nondestructive inspection, quality assurance testing, structural health monitoring, and providing a material state awareness. This Special Issue of Applied Sciences covers all aspects of ultrasonic guided waves (e.g., phased array transducers, meta-materials to control wave propagation characteristics, scattering, attenuation, and signal processing techniques) from the perspective of modeling, simulation, laboratory experiments, or field testing. In order to fully utilize ultrasonic guided waves for these applications, it is necessary to have a firm grasp of their requisite characteristics, which include that they are multimodal, dispersive, and are comprised of unique displacement profiles through the thickness of the waveguide.
