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Ascaris: The Neglected Parasite
Parasitic nematodes cause substantial morbidity and mortality in animals and people globally and major losses to food production annually. Ascaris is among the commonest geohelminths of swine and people worldwide, and causes major disease and socioeconomic losses, particularly in developing countries. The control of ascariasis has become a global health and welfare priority, but current treatment programs carry a significant risk of inducing anthelmintic resistance. Therefore, there is a need to work toward the sustainable control of Ascaris/ascariasis, built on a solid understanding of its molecular biology and genetics. Recently, we reported the 273 megabase (Mb) draft genome of Ascaris su...
Human Migration
Studies are shown on many aspects of migration, population development, human genetics, archaeology, anthropology, biology, linguistics, and a broad range of genomic studies on migration and cultural and social structures in the past and present. Human migration started in Africa spread to Asia and other regions of our globe and was assessed by studies on ancient and contemporary mtDNA sequencing distributed from the artic to South America. The evolutionary consequences of the settlement of the Aleutian Islands, Samoyedic-speaking populations from Siberia; early human migrations in Gabon Africa, the Republic of Sakha (formerly, Yakutia), African migration to Europe during the twenty-first ce...
Design Studies and Intelligence Engineering
The technologies applied in design studies vary from basic theories to more application-based systems. Intelligence engineering also plays a significant role in design sciences such as computer-aided industrial design, human factor design, and greenhouse design, and intelligent engineering technologies such as computational technologies, sensing technologies, and video detection encompass both theory and application perspectives. Being multidisciplinary in nature, intelligence engineering promotes cooperation, exchange and discussion between organizations and researchers from diverse fields. This book presents the proceedings of DSIE 2022, the International Symposium on Design Studies and In...
Oilseeds
As the cultivation of brassica crops continues to contribute to western diets, new approaches to maximizing yields are welcome. This book presents chapters on various aspects of this issue, with a particular focus on canola crops and the oil produced from them. Those chapters address the relevance of transgenic and molecular breeding techniques to develop cold tolerance in Brassica napus L. crops grown over the winter in North America, the effects of seed-placed ammonium sulphate and monoammonium phosphate on the germination and growth of brassicae oilseed crops and the cultivation of high-erucic Brassicaceae in a Mediterranean environment. Other chapters cover oil presses, sesame seeds and oilseed pests, as well as the nitrogen efficiency of oilseed rape.
Bioinformatics Research and Applications
This book constitutes the refereed proceedings of the 11th International Symposium on Bioinformatics Research and Applications, ISBRA 2015, held in Norfolk, VA, USA, in June 2015. The 34 revised full papers and 14 two-page papers included in this volume were carefully reviewed and selected from 98 submissions. The papers cover a wide range of topics in bioinformatics and computational biology and their applications.
Contemporary High Performance Computing
Contemporary High Performance Computing: From Petascale toward Exascale focuses on the ecosystems surrounding the world’s leading centers for high performance computing (HPC). It covers many of the important factors involved in each ecosystem: computer architectures, software, applications, facilities, and sponsors. The first part of the book examines significant trends in HPC systems, including computer architectures, applications, performance, and software. It discusses the growth from terascale to petascale computing and the influence of the TOP500 and Green500 lists. The second part of the book provides a comprehensive overview of 18 HPC ecosystems from around the world. Each chapter i...
[ ] With Design: Reinventing Design Modes
This collection stems from the International Association of Societies of Design Research (IASDR) congress in 2021, promoting the research of design in its many fields of application. Today's design finds itself at a critical moment where the conventional ‘modes’ of doing, thinking and application are increasingly challenged by the troubled ideology of globalisation, climate change, migration patterns and the rapid restructuring of locally driven manufacturing sectors. The volume presents a selection of papers on state-of-the-art design research work. As rapid technological development has been pushing and breaking new ground in society, the broad field of design is facing many unpreceden...
A Mixture Model Approach to Empirical Bayes Testing and Estimation
Many modern statistical problems require making similar decisions or estimates for many different entities. For example, we may ask whether each of 10,000 genes is associated with some disease, or try to measure the degree to which each is associated with the disease. As in this example, the entities can often be divided into a vast majority of "null" objects and a small minority of interesting ones. Empirical Bayes is a useful technique for such situations, but finding the right empirical Bayes method for each problem can be difficult. Mixture models, however, provide an easy and effective way to apply empirical Bayes. This thesis motivates mixture models by analyzing a simple high-dimensional problem, and shows their practical use by applying them to detecting single nucleotide polymorphisms.
