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In Cold-War Eastern Europe, Eddy's Bar is a magnet for the elite. They keep one another's secrets, even about a murder. When a young journalist learns the truth, he has to flee the country, and starts a new life, without family, money, or language, as a refugee in Canada.
Ripe with love, money, and power, the story of 35-year-old Rudolf--set in a fast-paced, urban environment--begs the question Do we only think we exist? Rudolf and his wife work day and night hoping for a better life--he is a philosophy graduate student and the manager of a car dealership. He also keeps up a heart-wrenching relationship with the chic Wanda. Then there is Nina, who studies logic but is secretly a prostitute, and Alfred, owner of a car-leasing company, seemingly upright, but actually an embezzler. Each character conceals something. Be it in Hungary or North America, the craving for existential clarity remains strong.
This book constitutes the refereed proceedings of the international Joint Modular Languages Conference, JMLC 2003, held in Klagenfurt, Austria in August 2003. The 17 revised full papers and 10 revised short papers presented together with 5 invited contributions were carefully reviewed and selected from 47 submissions. The papers are organized in topical sections on architectural concepts and education, component architectures, language concepts, frameworks and design principles, compilers and tools, and formal aspects and reflective programming.
From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development...
The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Thro...
A collection of poems by Romanian-Hungarian poet and novelist, Zoltán Böszörményi. This poetry is quite current in approach and content but also reflects that special Eastern European angst that has accumulated in the collective consciousness of the region over its turbulent history. However, the alternation between free verse and formal style is entirely due to the fact that Hungarian language allows for an infinite variety of rhyme pairs and any form of meter, and much of contemporary Hungarian poetry is still produced in conventional form. For this book the selected poems were grouped not by style but by theme; the first part containing meditative poems, the second part devoted to personal/lyrical poems, and the third to poems inspired by or dedicated to other poets and writers. Various styles and forms are represented in each cycle; only outstanding quality and significant content were considered for inclusion.
The goal of this book is to provide an introduction to the practical use of mobile NMR at a level as basic as the operation of a smart phone. Each description follows the same didactic pattern: introduction, basic theory, pulse sequences and parameters, beginners-level measurements, advanced-level measurements, and data processing. Nuclear Magnetic Resonance (NMR) spectroscopy is the most popular method for chemists to analyze molecular structures while Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool for medical doctors that provides high-contrast images of biological tissue depicting the brain function and the beating heart. In both applications large super-conducting mag...
This book has a chapter dedicated to each aspect of replication. The new features of PostgreSQL 9 are introduced and there are lots of practical examples and screenshots.""PostgreSQL Replication"" is ideal for PostgreSQL administrators who want to set up and understand replication. If you want to make your databases more robust, more secure, faster, and more scalable, you will find all the information you need in this single book focusing exclusively on PostgreSQL replication. It is assumed that you already have some basic experience with PostgreSQL.
In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.
Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis :Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 1 includes sections on assessing IDPs in the living cell,NMR based techniques, vibrational spectroscopy, and other spectroscopic techniques. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.