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Abstract: Allogeneic hematopoietic stem cell transplant remains the only curative treatment for myelofibrosis. Most post-transplantation events occur during the first two years and hence we aimed to analyze the outcome of 2-year disease-free survivors. A total of 1055 patients with myelofibrosis transplanted between 1995 and 2014 and registered in the registry of the European Society for Blood and Marrow Transplantation were included. Survival was compared to the matched general population to determine excess mortality and the risk factors that are associated. In the 2-year survivors, disease-free survival was 64% (60-68%) and overall survival was 74% (71-78%) at ten years; results were better in younger individuals and in women. Excess mortality was 14% (8-21%) in patients aged
This book shows the effect philanthropy can have in transferring technology in transitional societies that are turning themselves upside down. It further demonstrates that retraining of people and changing their "mindset" are as important as the technology itself.
Company towns, i.e., towns that developed around a single major industrial enterprise like General Motors or Siemens, mark the relationship between the expansion of production and the organization of a region in an entirely new way, the aim, above all, being the perfection of more or less complex forms of social organization. In addition to providing a general overview that will identify the basis of the problem within a historical framework, from the beginning of the industrial age to the establishment of Ford's archetype assembly line, the study concentrates on certain significant cases. The research then encounters real and virtual examples ranging from entertainment cities like Disneyworld to the Internet. These phenomena impose themselves on us as new models of the relationship between business, society and region, often altering our day-to-day habits in the process.
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This is a collection of papers from a 1997 conference that attempted to assess the Andrew W. Mellon Foundation's efforts to modernize Eastern European libraries after the fall of communism. Looking primarily at Hungary, Poland, the Czech Republic, and Slovakia, the international panel of contributors cover library automation, library policy, and management strategy.