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Telomeres
  • Language: en
  • Pages: 654

Telomeres

  • Type: Book
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  • Published: 2025-02-05
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  • Publisher: CRC Press

This book provides a comprehensive overview of aging and its mechanisms through the prism of telomere length and its link to lifestyle parameters and environmental pollutants, diseases where telomere length attrition is prominent, and therapeutic approaches to slow down or prevent the process of telomere length reduction. It also provides an extensive comparison of the methodology for telomere length determination and characterization. The book will help researchers in any discipline to obtain an in-depth and broad knowledge of the most recent advances in telomere research written by specialists in the field. It is also addressed to the readers interested in gaining an insight into the processes of aging and those factors that affect “graceful” aging, enabling them to extract even useful tips in improving their everyday habits.

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure
  • Language: en
  • Pages: 686

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

  • Type: Book
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  • Published: 2021-08-01
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  • Publisher: Elsevier

Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, ...

Emerging Social Issues on Targeted Drug Delivery
  • Language: en
  • Pages: 341

Emerging Social Issues on Targeted Drug Delivery

The world of targeted drug delivery (TDD) represents an incredible leap forward in how we treat and manage diseases . It’s a frontier where science converges with hope, precision, and, in many ways, a reimagining of healthcare itself. As we move closer to realizing a future where therapies can target specific cells or tis-sues with minimal side effects, the excitement is tempered by a growing recogni-tion of the technical, ethical, and societal challenges that come with this revolu-tionary shift in medical practice. In this drawing from the insights of re-searchers and thinkers who are deeply engaged in navigating this transformative field. Together, the following chapters, illustrate how the evolving landscape of TDD holds both immense promise and significant complexity.

Autoimmune and Autoinflammatory Diseases: from Genes to Metabolites in the Discovery of Predictive, Diagnostic and Therapeutic Targets.
  • Language: en
  • Pages: 177

Autoimmune and Autoinflammatory Diseases: from Genes to Metabolites in the Discovery of Predictive, Diagnostic and Therapeutic Targets.

Autoimmune and autoinflammatory diseases are increasingly being recognized as an important health challenge with a significant impact on patient’s quality of life. Early diagnosis is a key determinant of the progression and proper management of these diseases. Ongoing research advancements have led to the implementation of omics techniques, such as genomics and metabolomics, to identify disease biomarkers that could serve as potential diagnostic and therapeutic targets. However, their translation to clinical practice is being hampered by the lack of validated and reproducible results. In addition, the unraveling of the aetiopathogenetic mechanisms leading to the onset of these diseases will provide new insights in the prevention, prediction and treatment of autoimmune and autoinflammatory diseases.

Preventing War and Promoting Peace
  • Language: en
  • Pages: 369

Preventing War and Promoting Peace

Preventing War and Promoting Peace focuses on how health professionals can actively engage in the prevention of war and the promotion of peace.

Earth Song Cookbook
  • Language: en
  • Pages: 198

Earth Song Cookbook

Earth's Simple Guide to Health through Food contains a wealth of information on health, diet, alternative medicine, natural food presentation, and recipes, researched by an expert in the field. Readers will learn how to apply food as medicine and the learn how to adjust the contemporary diet to; treat illness and nervous disorders through food, and make the transition to whole vegetable foods.

Biomarkers in Toxicology
  • Language: en
  • Pages: 1160

Biomarkers in Toxicology

This handbook of the series Biomarkers in Disease informs comprehensively about all aspects of monitoring and detecting toxicity in the human body and model organisms. Biomarkers for assessing toxicity in diverse organs are presented and different assays and methods are explained. Single compounds and drugs and their toxicity for humans are shown and the methods for detection described. Similar to all the volumes of the Biomarkers in Disease series, the chapters are written by experts in their field, each chapter features key facts summarizing the most important aspects of its respective topic and the definitions of words and terms facilitate the reading and understanding. This handbook is a must-have for researchers in toxicology and biomedicine who analyze the effects of drugs and various other substances in the human body and in model organisms. It also serves as a thorough guide for clinicians and pharmacologists.

Pesticides
  • Language: en
  • Pages: 462

Pesticides

Pesticides are supposed to complete their intended function without "any unreasonable risk to man or the environment". Pesticides approval and registration are performed "taking into account the economic, social and environmental costs and benefits of the use of any pesticide". The present book documents the various adverse impacts of pesticides usage: pollution, dietary intake and health effects such as birth defects, neurological disorders, cancer and hormone disruption. Risk assessment methods and the involvement of molecular modeling to the knowledge of pesticides are highlighted, too. The volume summarizes the expertise of leading specialists from all over the world.

EU Food Law
  • Language: en
  • Pages: 433

EU Food Law

  • Categories: Law

In recent years, food law has taken on an increasingly prominent role in political discourse, with calls for a more sustainable food system challenging the legal status quo. A thorough legal perspective is thus indispensable for grasping the complexities of the EU food system and political quests for change. In the first monograph of its kind, Hanna Schebesta and Kai Purnhagen offer an authoritative and comprehensive overview of EU food legislation. Drawing on the authors' experience researching and teaching in the field, EU Food Law explores how political paradigms have shaped the development of laws in a variety of domains, including food technology, food safety, food information, food qua...

Serum Metabolites in Diagnostics and Therapeutics
  • Language: en
  • Pages: 132

Serum Metabolites in Diagnostics and Therapeutics

Metabolomics can critically assess key metabolic pathways and thus provide data for nutritional deficiencies, metabolic imbalance, environmental burden, and the gut microbiome. Since the metabolite functions are not determined by epigenetic regulation or post-translational modification, quantification and evaluation of metabolites is an highly effective method to capture time-dependent fluctuations and cellular metabolic state, even prior to disease onset. Blood serum is a primary carrier of small molecules in the body, present in the blood of every tissue and organ in the body. It plays a critical role in transporting dissolved gases, nutrients, hormones and metabolic wastes, as well as in the regulation of the pH and ion composition of interstitial fluids, the restriction of fluid losses at injury sites and the defence against toxins and pathogens.