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This book presents the laboratory, scientific and clinical aspects of nanomaterials used for medical applications in the fields of regenerative medicine, dentistry and pharmacy. It gives a broad overview on the in vitro compatibility assessment of nanostructured materials implemented in the medical field by the combination of classical biological protocols and advanced non-destructive nano-precision techniques with special emphasis on the topographical, surface energy, optical and electrical properties. Materials in the physical form of nanoparticles, nanotubes, and thin films are addressed in terms of their toxicity. The different pillars of the Nanomedicine field are also highlighted. The book takes an interdisciplinary approach of medicine, biology, pharmacy, physics, chemistry, engineering, nanotechnology and materials science. The international group of authors specifically chosen for their distinguished expertise belong to the academic and industrial world in order to provide a broader perspective. It appeals to researchers and graduate students.
Innovations in Nanoscience and Nanotechnology summarizes the state of the art in nano-sized materials. The authors focus on innovation aspects and highlight potentials for future developments and applications in health care, including pharmaceutics, dentistry, and cosmetics; information and communications; energy; and chemical engineering. The chapters are written by leading researchers in nanoscience, chemistry, pharmacy, biology, chemistry, physics, engineering, medicine, and social science. The authors come from a range of backgrounds including academia, industry, and national and international laboratories around the world. This book is ideally suited for researchers and students in chemistry, physics, biology, engineering, materials science, and medicine and is a useful guide for industrialists. It aims to provide inspiration for scientists, new ideas for developers and innovators in industry, and guidelines for toxicologists. It also provides guidelines for agencies and government authorities to establish safe working conditions.
The German lacuna in Edward Said’s 'Orientalism' has produced varied studies of German cultural and academic Orientalisms. So far the domains of German politics and scholarship have not been conflated to probe the central power/knowledge nexus of Said’s argument. Seeking to fill this gap, the diplomatic career and scholarly-literary productions of the centrally placed Friedrich Rosen serve as a focal point to investigate how politics influenced knowledge generated about the “Orient” and charts the roles knowledge played in political decision-making regarding extra-European regions. This is pursued through analyses of Germans in British imperialist contexts, cultures of lowly diplomat...
Recently the history of science in early modern Europe has been both invigorated and obscured by divisions between scholars of different schools. One school tends to claim that rigorous textual analysis provides the key to the development of science, whereas others tend to focus on the social and cultural contexts within which disciplines grew. This volume challenges such divisions, suggesting that multiple historical approaches are both legitimate and mutually complementary."--
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.
This book presents the overall vision and research outcomes of Nano-Tera.ch, which is a landmark Swiss federal program to advance engineering system and device technologies with applications to Health and the Environment, including smart Energy generation and consumption. The authors discuss this unprecedented nation-wide program, with a lifetime of almost 10 years and a public funding of more than 120 MCHF, which helped to position Switzerland at the forefront of the research on multi-scale engineering of complex systems and networks, and strongly impacted the Swiss landscape in Engineering Sciences.
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.
A review of the current state of the art of biomimetics, this book documents key biological solutions that provide a model for innovations in engineering and science. Leading experts explore a wide range of topics, including artificial senses and organs; mimicry at the cell-materials interface; modeling of plant cell wall architecture; biomimetic composites; artificial muscles; biomimetic optics; and the mimicking of birds, insects, and marine biology. The book also discusses applications of biomimetics in manufacturing, products, medicine, and robotics; biologically inspired design as a tool for interdisciplinary education; and the biomimetic process in artistic creation.
Two groups which originated in Nashville: Tennessee, in the early 1920's had a strong influence on American letters. Known as the "Fugitives" and “Agrarian,” they included, among others, John Crowe Ransom, Allen Tate, Robert Penn Warren, Donald Davidson and Merrill Moore. This study of their contributions is, as R.W.B. Lewis has written, “a searching, supple, and most of the time brilliantly precise account of thee writing, ideas, and attitudes of several of this century’s most interesting men of letters. The book achieves a kind of finality in the handling of its subject.” Mr. Stewart concentrates on the ideas, styles, themes, and widespread influence of the two groups, rather tha...
Audisee® eBooks with Audio combine professional narration and text highlighting for an engaging read aloud experience! Northern rockhopper penguins and colorful pufflegs are two examples of endangered birds. Few of them exist in the wild. Other birds have already gone extinct. What hurts these animals? What can you do to help? Read this book to find out!