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Glycochemistry
US, Canadian, and Chinese chemists summarize recent research into the synthesis, principles, and applications of carbohydrates for graduate students and researchers in carbohydrate chemistry, biochemistry, medicinal chemistry, and glycobiology. The topics include solid phase oligosaccharide synthesis, the chemical synthesis of bioactive steroidal saponins, the chemistry and biology of multi-valent saccharide displays, structures and mechanisms of action of aminoglycoside antibiotics, synthesizing glycosaminoglycans, glycosyltransferases in oligosaccharide synthesis, and metabolic substrate engineering as a tool for glycobiology Glycochemistry: Principles, Synthesis, and Applications presents methods used in the development of carbohydrate-based therapeutics. It highlights applications in chemical and enzymatic synthesis of complex carbohydrates, carbohydrate function, and carbohydrate-mediated biological recognition processes. There are practical examples on the development of carbohydrate-based pharmaceuticals and polymers for commercial use. The text also emphasizes the role of carbohydrates as key elements in modern molecular recognition processes.
Essentials of Glycobiology
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Meeting the Challenge
"Astronomy was the earliest science in which women's participation has been recorded. Enheduanna, the Mezopotanian priestess around 2350 BCE monitored the stars and Hypathia in the fourth century is especially famous. Women astronomers such as Sophia Brahe, Maria Cunitz, Elisabetha Hevelius, Maria Margaretha Kirch, and Caroline Herschel often worked alongside family members, husbands or brothers. The next generations were more independent, of them, Mary Somerville, Maria Mitchell, Williamina Fleming, and Nancy Grace Roman are mentioned. Vera C. Rubin had revolutionary ideas about the black holes whose real significance is recognized today. Jocelyn Bell Burnell helped in the discovery of pulsars for which her professor received the Nobel Prize. France A. Cordova was elevated to various top administrative positions. Finally, the astronomer Andrea M. Ghez received a share of the physics Nobel Prize for her work on black holes"--
Click Chemistry
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Information and Communications
Since publication of the National Research Council (NRC) reports on chemistry in 1985 and chemical engineering in 1988,1,2 dramatic advances in information technology (IT) have totally changed these communities. During this period, the chemical enterprise and information technology have enjoyed both a remarkably productive and mutually supportive set of advances. These synergies sparked unprecedented growth in the capability and productivity of both fields including the definition of entirely new areas of the chemical enterprise. The chemical enterprise provided information technology with device fabrication processes, new materials, data, models, methods, and (most importantly) people. In t...
Modern Methods in Carbohydrate Synthesis
Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important...
Introduction to BioMEMS
The entire scope of the BioMEMS field-at your fingertipsHelping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabr
Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize II
Advances in Polymer Science enjoys a longstanding tradition and good reputation in its community. Each volume is dedicated to a current topic and each review critically surveys one aspect of that topic, to place it within the context of the volume. The volumes typically summarize the significant developments of the last 5 to 10 years and discuss them critically, presenting selected examples, explaining and illustrating the important principles and bringing together many important references of primary literature. On that basis, future research directions in the area can be discussed. Advances in Polymer Science volumes thus are important references for every polymer scientist as well as for other scientists interested in polymer science - as an introduction to a neighboring field, or as a compilation of detailed information for the specialist.
Glycobiology
In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the first of three in the Methods in Enzymology series, including Glycomics (vol. 416) and Functional Glycomics (vol. 417), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are designed to provide an introduction of new methods to a large variety of readers who would like to participate in and contribute to the advancement of glycobiology. The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses.
Biomedical Micro- and Nano-Robots in Disease Treatment
Comprehensive resource covering fundamentals at the micro and nano scales, technical advances in micro- and nanorobots, and their biomedical applications Biomedical Micro- and Nanorobots in Disease Treatment: Design, Preparation, and Applications provides foundational knowledge on the subject in the fields of biomaterials, nanotechnology, and biomedicine, discusses the applications of micro- and nanorobots in the cardiovascular, cancer, ophthalmic, orthopedic, gastrointestinal, and nervous system disease treatment, and addresses their biosafety, autonomous motion behavior, and future development trends. The two highly qualified authors comprehensively and systematically introduces the concep...
