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This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.
This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. /divAuthoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity.
A national study of social conditions on college campuses found that college officials were concerned about alcohol and drug abuse, crime, breakdown of civility, racial tensions, sex discrimination, and a diminishing commitment to teaching and learning. In response to those findings, this book proposes that both academic and civic standards be clarified and that the enduring values that undergird a community of learning be precisely defined. Six principles are presented that provide a formula for day-to-day decision making on the campus and define the kind of community every college and university should strive to be: (1) a purposeful community, (2) an open community, (3) a just community, (...
Expert perspectives on SDI theory and practice The spatial data infrastructure (SDI) concept continues to evolve and become an increasingly important element of the infrastructure that supports economic development, environmental management, and social stability. Because of its dynamic and complex nature, however, it remains a fuzzy concept
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Three stories. One timeless bond. The child. An eight-year-old boy, unusually mature for his age, knows there's more to life than being bullied by neighbourhood kids. Though his home isn't the safe haven he dreams of, he finds solace in the company of Lacey, a young girl who makes him glow from the inside whenever they're together. The janitor. A man in his mid-twenties, very quiet and reserved, wants nothing more than to be seen for who he is. His work as a janitor is satisfying enough, but other parts of his life are drowning him in misery. Feeling defeated and insecure, he withdraws further into himself-until someone unexpected comes along. Someone who makes him feel alive. The beggar. A ...
This superbly illustrated book provides a comprehensive overview of guided endodontics, a technology-driven, contemporary treatment approach that represents a paradigm shift in endodontics. Guided endodontics is now the proven, safe, predictable and, clinically, the most effective method for management of calcified root canals and root-end resection surgeries. This book covers detailed step-by-step digital treatment planning and the clinical application of static guides and dynamic navigation systems for, both, surgical and non-surgical endodontic treatment. In essence, this novel technology utilizes preoperative CBCT scans and intra-oral 3D scans as well as uniquely developed special software, for virtual planning of the endodontic treatment. This book delineates 3D printing, CBCT, digital impression systems, static guide designing with different software and clinical application of static and dynamic navigation in endodontics and much more. The concluding chapter addresses the future trends in 3D guidance in endodontics, in particular, and dentistry in general.
Racked the country since 1967. (from inner sleeve).
"In Trindad is the first photographic book to document the complex issues of post-colonial Trinidad identity primarily through visual means. Puerto Rican photographer Pablo Delano has over the period of a decade photographed ordinary Trinidadians at work, at play, at worship - in their homes, on the streets, and in their vocational niches. His reproduced black and white photographs capture the essence of a uniquely intercultural Caribbean people, paradoxically poised between oil and natural gas-driven postindustrial capital development and earlier rhythms keyed to seasons of Christian, Hindu, Muslim, Orisha, and secular festivity."--BOOK JACKET.