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Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory di...
This paper investigates the impact of the pilot phase of Paraguay's conditional cash transfer programme, Tekoporã, on the demand for healthcare and education, and how much of this impact was due to the cash transfers and/or due to changes in behaviour/preferences, possibly as an effect of other, non-monetary programme components such as the conditionalities and family support visits. It also explores the presence of externalities effects through a decomposition of the average treatment effect on the treated (ATT) into participation and externality effect. This decomposition was possible thanks to the use of two distinct comparison groups, one within the village and possibly exposed to the e...
O tsunami tecnológico do século XXI está transformando a sociedade, a economia e os territórios. São necessárias novas formas de articulação de atores que convivem nas cidades em busca de visões sólidas que permitam construir o futuro almejado. Este livro traz as metodologias recomendadas para a orquestração de ecossistemas a partir dos casos de Barcelona, na Espanha; de Medellín, na Colômbia; e do estado de Santa Catarina e da cidade de Porto Alegre, no Brasil. O objetivo é compartilhar experiências e metodologias que podem auxiliar na implementação dos chamados pactos de inovação em locais que desejam liderar a economia e a sociedade do conhecimento.
O livro aborda o processo educacional superior conjugando as dimensões da natureza do ser humano através de incentivos, pesquisas, exemplos reais e simulações, argumentos comprobatórios e reflexivos, tendo-se como referência o curso de Ciências Contábeis. Os autores provocam e argumentam sobre o que está posto no curso para refletir, aprender e auxiliar no constructo dos discentes e docentes diante da complexidade tão presente em pleno século XXI. Organizado em nove partes, inicia-se com a identificação, trajetórias, perspectivas e expectativas dos discentes em relação à educação, aprendizagem e futuro. A Parte 2 aponta a trajetória e as práticas didático-pedagógicas u...
This paper investigates the impact of the pilot phase of Paraguay's conditional cash transfer programme, Tekoporã, on the demand for healthcare and education, and how much of this impact was due to the cash transfers and/or due to changes in behaviour/preferences, possibly as an effect of other, non-monetary programme components such as the conditionalities and family support visits. It also explores the presence of externalities effects through a decomposition of the average treatment effect on the treated (ATT) into participation and externality effect. This decomposition was possible thanks to the use of two distinct comparison groups, one within the village and possibly exposed to the e...
Macao, the former Portuguese colony in southeast China, has a long and very interesting history of cultural interaction between China and the West. Held by the Portuguese from the 1550s until its return to China in 1999, Macao was up to the emergence of Hong Kong in the later nineteenth century the principal point of entry into China for all Westerners - Dutch, British and others, as well as Portuguese. The relatively relaxed nature of Portuguese colonial rule, intermarriage, the mixing of Chinese and Western cultures, and the fact that Macao served as a safe haven for many Chinese reformers at odds with the Chinese authorities, including Sun Yat-sen, all combined to make Macao a very different and special place. This book explores how Macao was formed over the centuries. It puts forward substantial new research findings and new thinking, and covers a wide range of issues. It is a companion volume to Macao - Cultural Interaction and Literary Representations.
Case reports and clinical trials conducted in various countries show, more and more frequently, a positive correlation between the presence of original teeth and prevalence of root caries in older age. Because this is a global trend, it is likely that the predicted increase in the worldwide elderly population may soon cause a significant increase in the number of people requiring effective means of preventing and treating root surface caries. In response to this development, a team of outstanding contributors has reviewed the most important aspects of root caries. This new volume presents their findings along with discussions of how to deal with this health issue that progressively affects the oral health balance. The chapters in this book are divided in four core parts: Epidemiology, Biological Determinants, Lesion Assessment and Features and Preventive and Operative Therapies. The collection of state-of-the-art articles provides a broad overview and will serve as a reference for clinicians as well as scientists and, hopefully, will encourage new research.
This book discusses important methodologies for developing statistical designs, sample surveys and evaluation designs.