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E. T. A. Hoffmann
The essays in this volume address a very broad range of E. T. A. Hoffmann’s most significant works, examining them through the lens of “transgression.” His writings, perhaps more than those of any other German Romantic, portrayed the “dark side” of existence, which the following essays investigate for an Anglophone audience.
The Catch
Insightful analysis of relationships between human communities and aquatic ecosystems of Europe from c. 500 to 1500 CE.
Immune Escape Pathways from the HBV Core18-27 CD8 T Cell Response are Driven by Individual HLA Class I Alleles
Abstract: Background and aims: There is growing interest in T cell-based immune therapies for a functional cure of chronic HBV infection including check-point inhibition, T cell-targeted vaccines or TCR-grafted effector cells. All these approaches depend on recognition of HLA class I-presented viral peptides. The HBV core region 18-27 is an immunodominant target of CD8+ T cells and represents the prime target for T cell-based therapies. Here, a high-resolution analysis of the core18-27 specific CD8+ T cell and the selected escape pathways was performed. Methods: HLA class I typing and viral sequence analyses were performed for 464 patients with chronic HBV infection. HBV-specific CD8+ T-cell...
Telephone Directory
None
Current Catalog
First multi-year cumulation covers six years: 1965-70.
