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Signaling Pathways in Liver Diseases
This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Supplies in one place all the information on this active and complex research topic and may stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room. Fills the need of surgeons to understand the molecular mechanisms in hepatology. Provides a quick and comprehensive overview.
Immune Escape Pathways from the HBV Core18-27 CD8 T Cell Response are Driven by Individual HLA Class I Alleles
Abstract: Background and aims: There is growing interest in T cell-based immune therapies for a functional cure of chronic HBV infection including check-point inhibition, T cell-targeted vaccines or TCR-grafted effector cells. All these approaches depend on recognition of HLA class I-presented viral peptides. The HBV core region 18-27 is an immunodominant target of CD8+ T cells and represents the prime target for T cell-based therapies. Here, a high-resolution analysis of the core18-27 specific CD8+ T cell and the selected escape pathways was performed. Methods: HLA class I typing and viral sequence analyses were performed for 464 patients with chronic HBV infection. HBV-specific CD8+ T-cell...
Quantum Collision Theory of Nonrelativistic Particles
This book introduces the scattering theory of nonrelativistic systems, a standard tool for interpreting collision experiments with quantum particles at energies not too high. The goal is to explore the interaction between particles and their properties. The authors cover the basics of the theory through a detailed discussion of elastic scattering using the stationary Schrödinger equation and the Lippmann-Schwinger equation. These remarks are supplemented by a consideration of the time-dependent formulation of scattering theory. Selection rules for effective cross sections due to symmetries conditioned by the structure of the interparticle forces and the scattering of spin-polarized particle...
Wintermoon Ice
Wintermoon Ice, set on present-day Earth, features Tessa Kivelson, an archaeologist who unexpectedly acquires a mirror and a journal from her long-dead grandmother, Suvi Markku. This find thrusts Tessa into danger from alien creatures called Polydactyls, and she turns to her exasperating neighbor Jakob Faircrow for help. He is a capable defender (and later, lover) but she finds his smug arrogance infuriating. Jakob and Tessa must put aside their differences long enough to discover why Suvi hid the mirror and why the Polys want it. The journal provides vital clues to Suvi's past life in Severnessa with Jakob's twin brother Lut -- a life that will shortly intersect with Tessa's, when a magic gateway blends past and present, and brings the two women face to face with the creator of the Polydactyls. Wintermoon Ice is a spellbinding tale of twos: two cites, two times, two brothers and two women, who must save their world from an unspeakable terror.
Mördaren gör intrång
Det starka skenet från gården syntes lång väg över skogstopparna. På avstånd såg det ut som en mindre festplats, men om man närmade sig märkte man att ljuset kom från en garageöppning. Ett upplyst garage med portarna öppna - likt en fälla gillrad i natten för den som gör intrång. "Mördaren gör intrång" är femte delen i Leif Woxlins rosade serie Hälsingedeckare.
