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Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases
This book in the two volume set provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting into autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focuses on the role of microbiota/probiotics and their distinct mechanisms exerted in management of autoimmune liver, skin, thyroid, rheumatic and myopathic diseases. This could help in better understanding to design therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest immunology, medical microbiology and nutritional sciences will value its contribution. Overall, the book gives a new dimensions and insight in the aspects of microbial role in autoimmune disease pathogenesis and therapeutic aspects.
The Gut-Skin Axis: Interaction of Gut Microbiome and Skin Diseases
More and more evidence has demonstrated that gut microbiome plays critical roles in modulating the development of diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The new conception ‘gut-skin axis’ refers to the bidirectional relationship between the gut microbiome and skin health. Several mechanisms, such as intestinal barrier, inflammatory mediators, and metabolites, have been proposed for gut-skin axis. Currently, there have been various studies regarding the presence of the gut-skin axis and its resulting inflammatory effect due to gut microbiome imbalance. In addition, dysbiosis of the skin and gut microbiota is also observed in skin disorders. Therefore, understanding the gut-skin axis, especially in terms of microbiome modulation, is important for the gut and skin health, which may lead to development of novel therapies for skin disease.
Advances in Celiac Disease
The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRDs that present with a wide range of clinical manifestations. They are manifested by symptoms of gastrointestinal tract disorders, as well as hematological, dermatological endocrinological, gynecological, rheumatological and nervous system. NCGS is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal sy...
Gut Microbiota in Aging and Chronic Diseases
This edited volume studies gut microbiota peculiarities in elderly, in senescence-related and environmental-related alterations of gut microbiota in chronic diseases. Aging, as a physiological process mediated through several regulatory pathways and transcription factors, is generally speaking associated to a relentless functional decline and increasing risk of chronic diseases. Growing data on gut microbiota quali-quantitative changes in aging gut, and the opportunity to study by advanced NGS and metabolomic technologies, now offers novel horizons to link such changes to disease risks and to theoretically the weapons for gut microbiota intervention as an effective therapeutic tool. Chapters...
Insights in Geriatric Medicine: 2021
We are now entering the third decade of the 21st Century, and, especially in recent years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Geriatric Medicine. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This editorial initiative of particular relevance, led by Dr Tzvi Dwolatzky, Specialty Chief Editor of the Geriatric Medicine section, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Geriatric Medicine.
Spiroplasma, Mycoplasma, Phytoplasma, and Other Genome-Reduced and Wall-Less Mollicutes: Their Genetics, Genomics, Mechanics, Interactions and Symbiosis with Insects, Other Animals and Plants
Genome-reduced, wall-less, and fastidious bacteria of the genera Spiroplasma, Mycoplasma, Phytoplasma and allies belonging to the class Mollicutes, are known for a number of unique microbiological features, which have prompted researchers to investigate their basic, applied, and medical aspects. They are mostly parasitic or symbiotic to a variety of animals and plants, living on or within the eukaryotic cells. Spiroplasmas, recognized by their characteristic spiral shape and active twitching motility, are associated with insects and/or plants. S. poulsonii causes remarkable reproductive phenotype, called male-killing, of their insect hosts. S. citri and S. kunkelii are notorious as devastati...
Ghislieri 2005-2010
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Cancer Entangled
Cancer Entangled explores the shifts that took place in Denmark around the millennium, when health promoters set out to minimize delays in cancer diagnoses in hope of improving cancer survival. The authors suggest a temporal reframing of cancer control that emphasizes the importance of focusing on how people – potential patients as well as health care professionals – experience and anticipate cancer before a diagnosis or a prediction has been made. This argument compellingly challenges and augments anthropological work on cancer control that has privileged attention to the productive role of science and technology and to life with cancer or cancer risk. By offering rich ethnographic insights into the introduction of the first cancer vaccine, cancer signs and symptoms, public discourses on delays, social class and care seeking, cancer suspicion in the clinic, as well as the work on fast-track referral – the book convincingly situates cancer control in an ethical registrar involving attention to acceleration and time, showing how cancer waiting times become an index of the "state of the nation".
