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Molecular Docking adalah simulasi komputer untuk memprediksi interaksi protein dan ligannya. Metode ini sering kali digabungkan dengan simulasi dinamika molekuler untuk mempelajari dinamika sebuah sistem molekul pada kondisi yang telah ditentukan. Penggunaan docking dapat diterapkan dalam bidang pangan fungsional. Meskipun pada dasarnya metode komputasi tidak mudah untuk pemula, sudah ada beberapa perangkat lunak yang dapat digunakan berkat tampilan antarmuka yang ramah pengguna. Buku ini menjelaskan bagaimana prinsip dasar dan tutorial melakukan analisis docking menggunakan perangkat lunak Autodock Vina, PyRx, Discovery Studio Visualizer, serta simulasi dinamika molekuler menggunakan YASARA. Dengan tampilan antarmuka dan urutan langkah demi langkah yang runtut, kami mengharapkan pembaca dengan kategori pemula dalam bidang biologi komputasi dapat mengikuti setiap tahapannya dengan mudah.
Buku ini disusun mengingat masih sedikitnya acuan tentang teknik pemilihan pakan yang berkualitas secara cepat dan tepat, maka perlu untuk membuat buku referensi tentang teknik pemilihan pakan berkualitas dan formulasi pakan unggas untuk membantu pembaca dalam aplikasinya di lapangan. Buku ini bermanfaat untuk masyarakat umum: mahasiswa, dosen, peternak rakyat, analis laboratorium pakan, dan pelaku industri pakan ternak.
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a...
The optimization of pharmacokinetic properties has become the bottleneck and a major challenge in drug research. There was, hence, an urgent need for a book covering this field in an authoritative, comprehensive, factual, and conceptual manner. In this work of unique breadth and depth, international authorities and practicing experts from academia and industry present the most modern biological, physicochemical, and computational strategies to achieve optimal pharmacokinetic properties in research series. These properties include gastrointestinal absorption, protein binding, brain permeation, and metabolic profile. Toxicological issues are, of course, also of utmost importance. In addition to its 33 chapters, the book includes a CD-ROM containing the invited lectures, oral communications and posters (in full version) presented at the Second LogP Symposium, 'Lipophilicity in Drug Disposition -- Practical and Computational Approaches to Molecular Properties Related to Drug Permeation, Disposition and Metabolism', held at the University of Lausanne in March 2000.n̓.
Infections that occur in the wound created by an invasive surgical procedure are generally referred to as surgical site infections (SSIs). SSIs are one of the most important causes of healthcare-associated infections (HCAIs). A prevalence survey undertaken in 2006 suggested that approximately 8% of patients in hospital in the UK have an HCAI. SSIs accounted for 14% of these infections and nearly 5% of patients who had undergone a surgical procedure were found to have developed an SSI. However, prevalence studies tend to underestimate SSI because many of these infections occur after the patient has been discharged from hospital. SSIs are associated with considerable morbidity and it has been ...
Would you like to be a veterinarian? Veterinarians are scientists who are doctors for animals. In this book, you get to be part of the veterinary team by using science to solve cases, learning about careers in veterinary medicine, and seeing how advances in animal health can help people too.Be the VET! Solve the Case!
The aim of this Special Issue is to publish high quality papers concerning poultry nutrition and the interrelations between nutrition, metabolism, microbiota and the health of poultry. Therefore, I invite submissions of recent findings, as original research or reviews, on poultry nutrition, including, but not limited to, the following areas: the effect of feeding on poultry meat end egg quality; nutrient requirements of poultry; the use of functional feed additives to improve gut health and immune status; microbiota; nutraceuticals; soybean meal replacers as alternative sources of protein for poultry; the effects of feeding poultry on environmental impacts; the use of feed/food by-products in poultry diet; and feed technology.
The book has offered the consumer behaviour theory with implementation on two local foods of Malang meatballs and Kediri Tofu. It has a good attempt in implementing the theory of consumer behaviour and clarifying the conceptual to be of wider concern to the reader. The book offer the insight consumers perspective approaches to understand what’s their behaviour performed towards local foods among the competitive food industries. This book presented a comprehensive explanation about consumer’s acceptance towards Malang meatballs and Kediri tofu among the huge presence of branded fast foods.
This book is designed as a laboratory guide for the food microbiologist, to assist in the isolation and identification of common food-borne fungi. We emphasise the fungi which cause food spoilage, but also devote space to the fungi commonly encountered in foods at harvest, and in the food factory. As far as possible, we have kept the text simple, although the need for clarity in the descriptions has necessitated the use of some specialised mycological terms. The identification keys have been designed for use by microbiologists with little or no prior knowledge of mycology. For identification to genus level, they are based primarily on the cultural and physiological characteristics of fungi g...