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The Forgotten Mines and Coal Towns of Thoms Run
This book documents the history of the coal mines and coal towns of Thoms Run hollow. Read about the development of coal towns Beechmont, Hickman, Federal, Burdine, and Presto, PA. Get a sense of where the mines and towns were located, and about life in the coal patches. Understand the tough life that miners had in rural Pennsylvania. Learn the rich history of how one little road supported so much coal production and the development of Collier Township, PA
Engineering Pittsburgh
Western Pennsylvania's infrastructure is renowned for traversing valleys, mountains, rivers and everything in between. Early surveying in the region delineated state and local boundaries that allowed for the mapping of canals, railroads and roadways. Engineers developed bridges, ground transportation systems and airports that linked Pittsburgh to the world. Frequently overflowing rivers transformed into reliable navigation passageways. Drinking water and wastewater treatment systems allowed development and population to flourish, leading to investments in iconic buildings. Join expert civil engineers and professionals as they narrate the story of Pittsburgh and the surrounding region's engineering triumphs.
Hormones, Brain and Behavior Online
Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the re...
Principles of Hormone/Behavior Relations
Principles of Hormone/Behavior Relations, Second Edition, provides an introduction to the underlying principles of endocrine regulation of behavior, a newly emerging area of research within neurobiology and endocrinology. It addresses the properties of hormone/behavior relations, including the influence of family background, timing issues, neuroanatomical features, cellular mechanisms, and the importance of environmental context and evolution. This new edition incorporates critical advances in the field, also including increased coverage of hormonal influences on food intake, and on the cardiovascular system. The addition of entirely new principles provides further coverage of epigenetics an...
Gender Dysphoria and Disorders of Sex Development
This book provides a state of the art review on the care and treatment of and current scientific knowledge on gender dysphoria (GD) and disorders of sex development (DSD). The book elucidates the history, the present situation, and the newest developments and future perspectives in both research on GD and DSD and the clinical management of individuals with GD and DSD of all ages. With contributions from a selection of leading scientists and established clinicians in the field of GD and DSD, this is a unique and comprehensive book focusing on the etiology and developmental trajectories of GD and DSD regarding gender identity development, psychiatric comorbidity, classification dilemmas, ethic...
New Rapid-acting Antidepressants
This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy. The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area. In this volume, a variety of novel pharmaceutical treatments are examined. This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments.
The Human Nervous System
The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function ro...
Morphophonemic Variability, Productivity, and Change
TRENDS IN LINGUISTICS is a series of books that open new perspectives in our understanding of language. The series publishes state-of-the-art work on core areas of linguistics across theoretical frameworks as well as studies that provide new insights by building bridges to neighbouring fields such as neuroscience and cognitive science. TRENDS IN LINGUISTICS considers itself a forum for cutting-edge research based on solid empirical data on language in its various manifestations, including sign languages. It regards linguistic variation in its synchronic and diachronic dimensions as well as in its social contexts as important sources of insight for a better understanding of the design of linguistic systems and the ecology and evolution of language. TRENDS IN LINGUISTICS publishes monographs and outstanding dissertations as well as edited volumes, which provide the opportunity to address controversial topics from different empirical and theoretical viewpoints. High quality standards are ensured through anonymous reviewing.
Psychiatric Disorders
Due to their prevalence, pervasiveness and burden inflicted on men and women of today, psychiatric disorders are considered as one of the most important, sever and painful illnesses. This impairment of cognitive, emotional, or behavioural functioning is in some cases tragic. Aside from knowing the physical organic factors, such as infections, endocrinal illnesses or head injuries, the aetiology of psychiatric disorders has remained a mystery. However, recent advances in psychiatry and neuroscience have been successful in discovering subsequent pathophysiology and reaching associated bio-psycho-social factors. This book consists of recent trends and developments in psychiatry from all over th...
Brain, Behavior and Epigenetics
Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similaritie...
