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The Fundamental Biology of Basophils in Health and Disease
  • Language: en
  • Pages: 161

The Fundamental Biology of Basophils in Health and Disease

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Novel Insights into Inflammatory Roles of Mast Cells and Basophils
  • Language: en
  • Pages: 353
Tumor Microenvironment
  • Language: en
  • Pages: 226

Tumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, γδ T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more. Taken alongside its companion volumes, Tumor Microenvironment: Hematopoietic Cells – Part B updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Microfluidic Organ-on-a-Chip: Revolutionary Platforms for Disease Comprehension and Treatment
  • Language: en
  • Pages: 176

Microfluidic Organ-on-a-Chip: Revolutionary Platforms for Disease Comprehension and Treatment

Existing culture systems have a limited ability to reproduce the complicated and dynamic microenvironment of a functioning organ. To solve the issues of conventional culture techniques, multidisciplinary researchers, involving medical doctors, stem cell and developmental biology experts, engineers and physical scientists, have emerged to innovate methods and devices. A microfluidic organ-on-a-chip (μOOC) is a cell culture device, based on microfluidic technology, which contains continuously perfused chambers with cells to simulate organ-level physiology/pathology. The μOOC is not to build a whole living organ, but rather to synthesize minimal functional units that recapitulate organ-/tissu...

Tumor Immunology and Immunotherapy - Cellular Methods Part B
  • Language: en
  • Pages: 586

Tumor Immunology and Immunotherapy - Cellular Methods Part B

Tumor Immunology and Immunotherapy - Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more.

Interleukin-33 Biology in Tissue Development, Homeostasis and Disease
  • Language: en
  • Pages: 235

Interleukin-33 Biology in Tissue Development, Homeostasis and Disease

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Novel Strategies of Anti-Tumor Vaccines
  • Language: en
  • Pages: 170
The Role of the Immune Response in Brain Metastasis
  • Language: en
  • Pages: 106

The Role of the Immune Response in Brain Metastasis

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Notch Signaling as a Regulator of Tumor Immune Response
  • Language: en
  • Pages: 193