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Gordon Fraser
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In Good Company
In Good Company is a graphic account by the Hon. William Fraser, Gordon Highlanders, of his service in the First World War. Several times wounded, he went to Flanders in 1914 with the 2nd Battalion and commanded successively a platoon, a company, a Territorial battalion and a Regular battalion, ending the war as a lieutenant-colonel of twenty-eight, having survived the battles of First, Second and Third Ypres, Arras, Cambrai and the final triumphs of 1918. Frasers letters and diaries from the front, which compose this absorbing book, were edited by his son, General Sir David Fraser, soldier, biographer, historian, novelist. They provide a vivid, often highly critical and virtually unbroken account of those extraordinary days, seen through the eyes of a young Highland office. In Good Company gives a remarkable insight into some of the most terrible and challenging years of the Armys life.
The Biology and Pathology of Innate Immunity Mechanisms
In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the...
Cellular Transplantation
There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted b...
Star Territory
The United States has been a space power since its founding, Gordon Fraser writes. The white stars on its flag reveal the dream of continental elites that the former colonies might constitute a "new constellation" in the firmament of nations. The streets and avenues of its capital city were mapped in reference to celestial observations. And as the nineteenth century unfolded, all efforts to colonize the North American continent depended upon the science of surveying, or mapping with reference to celestial movement. Through its built environment, cultural mythology, and exercise of military power, the United States has always treated the cosmos as a territory available for exploitation. In St...
Alcohol Use Disorders and the Lung
Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find...
Targeting of Drugs 6
Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997
Microbes as Tools for Cell Biology
Microbes as Tools for Cell Biology bridges the gap between cell biology and microbiology. This laboratory guide provides a microbial tool kit for biologists who wish to use microbes as probes for basic cellular functions. The volume is organized into three sections, covering essential information on culture and genetic manipulation of microbes, assays for pathogen-host recognition, and analysis of intracellular parasitism. Each chapter outlines practical procedures and describes the rationale behind their development. This volume should prove useful to anyone interested in the biology of infectious agents, or their exploitation as a new generation of cell biological reagents.Key Features* Introduction by renowned microbiologist Dr. Stanley Falkow* Covers manipulation of pathogens, especially generation and selection of non-virulent phenotypes* Guides researchers in the study of intracellular pathogenesis* Describes microbial adherence and phagocytosis assays* Focuses on protein trafficking in infected cells* Well-illustrated with color plates, halftones, and diagrams
Macrophages and Related Cells
To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macropha...
