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Radiotracers in Drug Development
Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the b
Clinical Pharmacology: Current Topics and Case Studies
This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry.
Old Alexandria, Bonhill and Renton
Excellent pictures of the streets and shops of Alexandria, Bonhill and Renton are coupled with photographs of the local factories. An aerial view shows the various print- and dyeworks that were situated along the banks of the Leven, and there are several pictures of the ornate Argyll Motor Works, with their opulent marble offices. Renton Bowling Club, children paddling in the river, trams in Main Street, Bonhill Bridge and a fire at the yarn warehouse at Dillichip works are some of the other pictures featured.
Radiotracers in Drug Development
Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the b
Pharmacokinetics in Drug Development
The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.
Balloch and Around
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Comprehensive Coordination Chemistry II
Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.
Metal Ions in Biological Systems
Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volumes deal with such topics as the formation, stability, structure, and reactivity of biological compounds of low and high molecular weight containing metal ions; the metabolism and transport of metal ions and their complexes; and new models of complicated natural structures and processes. Devot...
Writing Romantic Climate Change
In the Romantic period, women writers developed specific aesthetics and writing strategies in their engagements with climate change and climate catastrophe. Anya Heise-von der Lippe draws on intersectional feminist and ecocritical approaches to highlight gender as a complicating category in Romantic engagements with these topics. She addresses the ways in which gendered critical framings continue to resonate in current Anthropocene discourses that use Romantic conceptualizations of »Nature«, impacting contemporary approaches to the relationship between humans and non-humans in the ongoing climate catastrophe.
