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Exosomes and MicroRNAs in Biomedical Science
MicroRNAs (miRNAs) are a member of the family of non-coding RNA molecules, and consist of small conserved sequences between 19–25 nucleotides in length that are responsible for regulating many cellular functions by affecting a wide range of messenger RNAs in a sequence specific manner. Fundamental biological processes like cell proliferation and growth, stress resistance, tumorigenesis, fat metabolism, and neural development have all been shown to be governed by miRNAs. miRNAs carry out the post-transcriptional silencing of gene expression via targeting the 30-untranslated region (UTR) of the complementary mRNA sequence. The dysregulation of the expression levels of various miRNAs is typic...
Eat Like a Girl
NEW YORK TIMES BESTSELLER! INTERNATIONAL BESTSELLER! Discover how to harness the power of food to support your body’s natural rhythms, empowering you to heal and thrive in this cookbook based on the revolutionary international bestseller, Fast Like a Girl. Do you struggle with hormonal imbalances or feel like your diet is out of sync with your body’s needs? Do you find it difficult to manage your energy levels throughout the month? Many women experience these challenges, often without understanding why. This book will show you how to use food as a powerful tool to support your body’s natural rhythms and guide you to a healthier, more balanced life. Thousands of women worldwide have emb...
The Role of non-coding RNAs in Gastrointestinal Cancers
Gastrointestinal malignancies encompass a large number of tumor types, and collectively are responsible for a significant portion of new cancer cases annually. According to the IARC database, colorectal cancer alone is responsible for approximately 10% of new cases of cancer worldwide annually. There is significant heterogeneity across the various tumor types, with different pathways and factors involved in oncogenesis, as well as varying degrees of prognosis depending on the tumor type. Non-coding RNAs (ncRNAs) contribute to a significant portion of the human transcriptome, and of particular interest are the micro-RNAs (miRNAs), long ncRNAs (lncRNAs), and circular ncRNAs (circRNAs). With the advent of next-generation sequencing and new technologies such a minimally invasive biopsy techniques, there is a growing body of evidence elucidating the role of ncRNAs in the progression of various form of gastrointestinal cancers. Furthermore, in addition to their relevance to cancer progression, these ncRNAs have important potential as biomarkers and prognostic markers for various GI cancers.
Diet and Nutrition in Neurological Disorders
Diet and Nutrition in Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With coverage of different types of diets, including Mediterranean or DASH, this broad coverage allows readers to learn about diets and their affect on specific disorders which may well be relevant to other conditions. This includes diseases such as Alzheimer's, Parkinson's, ALS, MS and severe neurological conditions such as brain injury, stroke, headache and migraine. This volume provides a platform for research on new dietary regimes and on future investigations of diet and nutrition. - Summarizes diet and nutrition research for a variety of neurological conditions - Contains chapter abstracts, key facts, dictionary and summary - Covers diet in Alzheimer's Parkinson's, ALS, MS, and more - Includes conditions like migraine, headache, stroke, and brain injury - Discusses the Mediterranean diet in the context of brain health
Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment
In line with recent evidence, the development of cancer has been described as uncontrolled cell growth that results from gradual accumulation of genetic and epigenetic alterations, involving aberrations in oncogenes, tumor suppressor genes, and defects in genes engaged in DNA repair. As a result, cancer cells acquire a neoplastic phenotype and tumor-associated antigens (TAAs) are presented on their surface. These target structures should be recognized by cells of the immune system. However, a sequence of events at the genetic and epigenetic level disturb immune cells, and in consequence, make them unable to eliminate cancer cells. Both innate and adaptive immunity are mobilized against cance...
Carnivore Cure: Meat-Based Nutrition and the Ultimate Elimination Diet to Attain Optimal Health
Carnivore Cure is the first elimination protocol to explain how to adopt a meat-based diet to bring about healing. Get back to optimal health by finding the perfect foods to fuel your individual body. Most elimination diets work to an extent but fail to consider all the individual, physical symptoms, and food sensitivities. Most elimination diets remove processed foods and additives but fail to remove plant-based toxins that can contribute to disease. Until now. Introducing, Carnivore Cure. You start with meats that have the least number of allergens and sensitivities. Once you reach a baseline of health, then you can incorporate other meats that may have previously caused a sensitivity. As ...
