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Perilous Chastity
Bearing such titles as The Doctor's Visit or The Lovesick Maiden, certain seventeenth-century Dutch paintings are familiar to museum browsers: an attractive young woman—well dressed, but pale and listless—reclines in a chair, languishes in bed, or falls to the floor in a faint. Weathered crones or impish boys leer suggestively in the background. These paintings traditionally have been viewed as commentary on quack doctors or unmarried pregnant women. The first book to examine images of women and illness in the light of medical history, Perilous Chastity reveals a surprising new interpretation. In an engaging analysis enhanced by abundant illustrations-including eight pages of color plate...
The Draw of the Alps
The Alps have exerted a hold over the German cultural imagination throughout the modern period, enthralling writers, artists, philosophers, scientists, and tourists alike. The Draw of the Alps interrogates the dynamics of this fascination. Though philosophical and aesthetic responses to Alpine space have shifted over time, the Alps continue to captivate at an individual and collective level. This has resulted in myriad cultural engagements with Alpine space, as this interdisciplinary volume attests. Literature, photography, and philosophy continue to engage with the Alps as a place in which humans pursue their cognitive and aesthetic limits. At the same time, individuals engage physically wi...
Nostalgia in Transition, 1780-1917
Referred to long ago as a "disease" of Swiss soldiers and Highland regiments far from home, nostalgia became known in the 1920s as more of a fleeting rather than debilitating condition. Yet what caused this shift in our collective understanding of the term? In Nostalgia in Transition, 1780-1917, Linda M. Austin traces the development of nostalgia from a memory disorder in the eighteenth century to its modern formulation as a pleasant recreational distraction. Offering a paradigm for and analysis of nostalgic memory as it operates in various attempts to reenact the past, Austin explains both the early and the modern understanding of this phenomenon. Beginning with an account of nostalgia's tr...
War Neurology
Interest in the history of neurological science has increased significantly during the last decade, but the significance of war has been overlooked in related research. In contrast, this book highlights war as a factor of progress in neurological science. Light is shed on this little-known topic through accounts given by neurologists in war, experiences of soldiers suffering from neurological diseases, and chapters dedicated to neurology in total and contemporary war. Written by experts, the contributions in this book focus on the Napoleonic Wars, the American Civil War, the Franco-Prussian War of 1870, World Wars I and II, and recent conflicts such as Vietnam or Afghanistan. Comprehensive yet concise and accessible, this book serves as a fascinating read for neurologists, neurosurgeons, psychiatrists, historians, and anyone else interested in the history of neurology.
The Politics of the Marvel Cinematic Universe
The Marvel Cinematic Universe (MCU) is the most expansive and widely viewed fictional narrative in the history of cinema. In 2009, Disney purchased Marvel Entertainment for $4 billion, including its subsidiary film production company, Marvel Studios. Since then, the MCU—the collection of multimedia Marvel Studios products that share a single fictional storyline—has grown from two feature films to thirty interconnected movies, nine streaming Disney+ series, a half dozen short films, and more than thirty print titles. By 2022, eight of the twenty-five highest grossing films of all time are MCU movies. The MCU is a deeply political universe. Intentionally or not, the MCU sends fans score...
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Point-of-care System for HTLV-1 Proviral Load Quantification by Digital Mediator Displacement LAMP
Abstract: This paper presents a universal point-of-care system for fully automated quantification of human T-cell lymphotropic virus type 1 (HTLV-1) proviral load, including genomic RNA, based on digital reverse RNA transcription and c-DNA amplification by MD LAMP (mediator displacement loop-mediated isothermal amplification). A disposable microfluidic LabDisk with pre-stored reagents performs automated nucleic acid extraction, reaction setup, emulsification, reverse transcription, digital DNA amplification, and quantitative fluorogenic endpoint detection with universal reporter molecules. Automated nucleic acid extraction from a suspension of HTLV-1-infected CD4+ T-lymphocytes (MT-2 cells) yielded 8 ± 7 viral nucleic acid copies per MT-2 cell, very similar to the manual reference extraction (7 ± 2 nucleic acid copies). Fully automated sample processing from whole blood spiked with MT-2 cells showed a comparable result of 7 ± 3 copies per MT-2 cell after a run time of two hours and 10 min
