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Hypertension: from basic research to clinical practice
Hypertension: from basic research to clinical practice” contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.
From Habitants to Immigrants: The Sansoucys, the Harpins, and the Potvins
From Habitants to Immigrants: The Sansoucys, the Harpins, and the Potvins, is the story of three French Canadian families, from the forays of the Carignan Salières Regiment in1665-66, to settlement in the Canadian wilderness, dependence on a family economy, the pain of epidemics and war, the loss of French Canada, the ensuing cultural conflicts, the end of available farmland, and finally, emigration to the mill towns of Massachusetts and the creation of a Franco-American diaspora across the United States. The chronicle of the Sansoucy, Harpin, and Potvin families reveals the strength of French Canadian families, parishes, and communities, their sorrows, limitations and joys. It is the story of generations of oppressed but resilient people in the context of the social, economic and political events of their times, their emigration and eventual assimilation as industrious and patriotic American citizens. The book contains oral histories, family letters, and photographs.
Cortical NO interneurons from embryogenesis to functions
Neuronal processing and physiology rely on a delicate interplay between glutamatergic excitatory neurons and GABAergic inhibitory interneurons in a spatially, temporally and cell-type specific manner. Understanding these processes is complicated further by the large diversity characterizing the cerebral cortex. Although recent advances have significantly improved our knowledge of its neuronal types, the identity and the roles of several subpopulations of GABAergic interneurons remain elusive. Presumably, because of their apparent paucity, their diversity, the highly labile nature of nitric oxide (NO) as well as its pleiotropic actions, the functional importance of NO-producing GABAergic interneurons is particularly enigmatic. This Research Topic will cover the different aspects of cortical NO interneurons, from their diversity, embryonic origins to their functions in the cortical circuit and physiology.
Hypertension and the Brain as an End-Organ Target
The first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer's. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging.
Advances in Brain Vascular Research
The brain vasculature nurtures and regulates basic functions of the central nervous system (CNS), acting as a barrier against pathogens. This book provides in-depth and focused data on the characteristics, function and role of brain blood vessels in health and disease. It addresses topics such as vascular activity, cell-cell communication, and the role of the endothelium in the development of the most prevalent types of cerebrovascular disease, neurodegenerative disorders, cognitive impairment, and vascular abnormalities. It offers an updated view of the current state of microvascular biology and research, and thus supports the discovery of new therapeutic agents and procedures directed at several CNS disorders.
Acadian Awakenings: New Brunswick
A one-name study of Girouard families who emigrated from France and settled in Canada and Louisiana.
The Wandering Princess
Helene was a strong-willed princess, raised in France but closely connected with the court of Queen Victoria. After the premature end to a romance with Victoria's grandson, she married into the royal family of Italy. However, Helene began extended adventuresome trips into Africa where she became a big-game hunter, explorer and travel writer, escaping from an unhappy marriage and the boredom of court life. Her travels took her around the world, but her sense of royal duty brought her back to nurse aboard a hospital ship in Libyan waters, then to an important role as head of the Italian Red Cross nurses during the First World War while her husband headed Italy's Third Army, and her two sons served in the artillery and the navy. Afterwards, her strong Italian nationalism made her an ally to Gabriele d'Annunzio and Benito Mussolini, but the disastrous Second World War saw her grandchildren interned in Austria and her older son die as a British prisoner-of-war while she continued her charitable work in Naples. When the country voted to become a republic in 1946, Helene was the only member of the royal family allowed to remain in Italy with her second 'secret' husband.
