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Modeling Discrete Time-to-Event Data
This book focuses on statistical methods for the analysis of discrete failure times. Failure time analysis is one of the most important fields in statistical research, with applications affecting a wide range of disciplines, in particular, demography, econometrics, epidemiology and clinical research. Although there are a large variety of statistical methods for failure time analysis, many techniques are designed for failure times that are measured on a continuous scale. In empirical studies, however, failure times are often discrete, either because they have been measured in intervals (e.g., quarterly or yearly) or because they have been rounded or grouped. The book covers well-established m...
Health Economics of Dementia
Drugs are being developed to alleviate the symptoms of dementia and different models of care are being tried. This book is a reference work in the subject. It gives a basis of the disease, its epidemiology, care implications, development and use of drugs. It discusses the challenges of obtaining reliable data and reviews the tools used to assess the costs of dementia to date. It also deals with the pharmacoeconomics of dementia.
Architectural Geometry
Architectural Geometry is the first book to introduce a revolutionary new approach to design. Geometry lies at the core of the architectural design process. It is omnipresent, from the initial form-finding stages to the actual construction. Modern constructive geometry provides a variety of tools for the efficient design, analysis, and manufacture of complex shapes. This results in new challenges for architecture. However, the architectural application also poses new problems to geometry. Architectural geometry is therefore an entire research area, currently emerging at the border between applied geometry and architecture. Written for students, architects, construction engineers, and industrial designers – Architectural Geometry is a source of inspiration for scientists interested in applications of geometry processing in architecture and art. With over 700 pages, including 2,100 full-color images of built architecture, architectural projects, and artwork, Architectural Geometry takes readers from basic to advanced geometry then leads them to the cutting-edge of research in the architectural geometry field.
Transporters as Drug Targets
As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.
The Falls of Rome
Focuses on the resilience of generations of Roman men and women, and their ability to reconstitute their city and society.
The Hofner Guitar
This book celebrates the glory years of Hofner, the company made famous by the Beatles' bassist Paul McCartney's use of their left-handed 1962 500/1 model. Beautifully illustrated in colour and black and white, the volume is packed with detailed information about classic Hofner guitars as well as interviews with Paul McCartney, David Gilmour, Ritchie Blackmore (of Deep Purple), Albert Lee, and others. The famous 'Memorabilia' chapter includes crisp reproductions of pages from the vintage Selmer catalogs (the UK's Hofner distributors and makers of high-quality guitar/bass amps and other instruments through 1993); a guide to dating Hofner guitars; and a wonderfully insightful interview with Christian Benker, the company's former managing director.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Electric Guitar
None
Exit-Voice Dynamics and the Collapse of East Germany
Winner of the Social Science History Association President’s Book Award East Germany was the first domino to fall when the Soviet bloc began to collapse in 1989. Its topple was so swift and unusual that it caught many area specialists and social scientists off guard; they failed to recognize the instability of the Communist regime, much less its fatal vulnerability to popular revolt. In this volume, Steven Pfaff identifies the central mechanisms that propelled the extraordinary and surprisingly bloodless revolution within the German Democratic Republic (GDR). By developing a theory of how exit-voice dynamics affect collective action, Pfaff illuminates the processes that spurred mass demons...
