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Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. ...
Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME 1
These proceedings contain a selection of refereed papers presented at or - lated to the Annual Workshop of the TYPES project (EU coordination action 510996), which was held during March 26–29, 2008 in Turin, Italy. The topic of this workshop, and of all previous workshops of the same project, was f- mal reasoning and computer programming based on type theory: languages and computerized tools for reasoning, and applications in several domains such as analysis of programming languages, certi?ed software, mobile code, formali- tion of mathematics, mathematics education. The workshop was attended by more than 100 researchers and included more than 40 presentations. We also had three invited lectures, from A. Asperti (University of Bologna), G. Dowek (LIX, Ecole polytechnique, France) and J. W. Klop (Vrije Universiteit, A- terdam, The Netherlands). From 27 submitted papers, 19 were selected after a reviewing process. Each submitted paper was reviewed by three referees; the ?nal decisions were made by the editors. This workshop is the last of a series of meetings of the TYPES working group funded by the European Union (IST project 29001, ESPRIT Working Group 21900, ESPRIT BRA 6435).
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Advances in forensic odontology have led to improvements in dental identification for individual cases as well as in disaster victim identification (DVI). New and updated technologies mean advances in bitemark analysis and age estimation. Growth in the field has strengthened missing persons networks leading to more and faster identifications of un
Advances in Immunology
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