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BALLISTICS 2014
Original research from around the world on weapons-grade projectiles, warheads, missiles, guns and their effects on target materialsNew information on shaped charges, fire, control strategies, simulation, blast resistance, non-lethal systems and more190 original presentations in two printed volumes, plus searchable CD The first part of this 2-volume set, part of an ongoing series, presents previously unpublished research on the design and modeling of ballistic devices ranging from shells to missiles, including explosives, propellants and internal components. The second part investigates the effects of ballistic penetrants on a variety of targets, including human models, as well as hard targe...
Multiscale Modeling and Simulation of Shock Wave-Induced Failure in Materials Science
Martin Oliver Steinhauser deals with several aspects of multiscale materials modeling and simulation in applied materials research and fundamental science. He covers various multiscale modeling approaches for high-performance ceramics, biological bilayer membranes, semi-flexible polymers, and human cancer cells. He demonstrates that the physics of shock waves, i.e., the investigation of material behavior at high strain rates and of material failure, has grown to become an important interdisciplinary field of research on its own. At the same time, progress in computer hardware and software development has boosted new ideas in multiscale modeling and simulation. Hence, bridging the length and time scales in a theoretical-numerical description of materials has become a prime challenge in science and technology.
Characterization of a Setup to Test the Impact of High-amplitude Pressure Waves on Living Cells
Abstract: The impact of pressure waves on cells may provide several possible applications in biology and medicine including the direct killing of tumors, drug delivery or gene transfection. In this study we characterize the physical properties of mechanical pressure waves generated by a nanosecond laser pulse in a setup with well-defined cell culture conditions. To systematically characterize the system on the relevant length and time scales (micrometers and nanoseconds) we use photon Doppler velocimetry (PDV) and obtain velocity profiles of the cell culture vessel at the passage of the pressure wave. These profiles serve as input for numerical pressure wave simulations that help to further quantify the pressure conditions on the cellular length scale. On the biological level we demonstrate killing of glioblastoma cells and quantify experimentally the pressure threshold for cell destruction
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