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Catecholamine Research in the 21st Century
  • Language: en
  • Pages: 8
Catecholamine Research in the 21st Century
  • Language: en
  • Pages: 9
Catecholamine Research in the 21st Century
  • Language: en
  • Pages: 8
Bioactive Peptides
  • Language: en
  • Pages: 512

Bioactive Peptides

  • Type: Book
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  • Published: 2009-04-23
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  • Publisher: CRC Press

Answering a long-standing need in the pharmaceutical and biotechnology fields, this definitive reference focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. It takes peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics. It presents the overall contribution peptide science has made to molecular, cellular, and whole organism biology, while discussing future targets and therapeutic applications. With the mounting worldwide interest in the therapeutic potential of peptides, this is an indispensable work for researchers.

Transition of Care
  • Language: en
  • Pages: 170

Transition of Care

Pediatricians face many questions and challenges during patients’ transition from childhood to adulthood. Chronic diseases justify long-term medical, psychological, educational, and social management. The establishment of networks with adult endocrinologists is, therefore, very important to achieving optimal conditions for a successful transition period. In this book, leading experts discuss major public health issues such as diabetes and obesity. They also review genetic diseases, including Turner syndrome and congenital adrenal hyperplasia. All clinical cases are presented in a focused way to highlight any issues which might be discussed by the doctor with patients and family. Psychological approaches are debated as are proposals for defining specific tools to encourage autonomy during this life period. This book is a valuable tool and will be helpful in answering many questions for endocrinologists, adult and pediatric, dedicated to the long-term management of patients with chronic diseases.

Polyglutamine Disorders
  • Language: en
  • Pages: 467

Polyglutamine Disorders

  • Type: Book
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  • Published: 2018-02-09
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  • Publisher: Springer

This book provides a cutting-edge review of polyglutamine disorders. It primarily focuses on two main aspects: (1) the mechanisms underlying the pathologies’ development and progression, and (2) the therapeutic strategies that are currently being explored to stop or delay disease progression. Polyglutamine (polyQ) disorders are a group of inherited neurodegenerative diseases with a fatal outcome that are caused by an abnormal expansion of a coding trinucleotide repeat (CAG), which is then translated in an abnormal protein with an elongated glutamine tract (Q). To date, nine polyQ disorders have been identified and described: dentatorubral-pallidoluysian atrophy (DRPLA); Huntington’s dise...

Interaction Between Neurons and Glia in Aging and Disease
  • Language: en
  • Pages: 524

Interaction Between Neurons and Glia in Aging and Disease

A superb source of reference reviews as well as a concise overview of the functional cross-talk between neurons and glial cells, this book also focuses on microglia and inflammation in the aging brain and in neurological disorders. The scientific spectrum covered by this book is of key interest, and is recognized by the scientific community as a major competitive area with critical implications for human health.

Facilitative Glucose Transporters in Articular Chondrocytes
  • Language: en
  • Pages: 96

Facilitative Glucose Transporters in Articular Chondrocytes

Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.

Neural Stem Cells and Therapy
  • Language: en
  • Pages: 456

Neural Stem Cells and Therapy

This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.

Gene Therapy of the Central Nervous System: From Bench to Bedside
  • Language: en
  • Pages: 372

Gene Therapy of the Central Nervous System: From Bench to Bedside

  • Type: Book
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  • Published: 2005-11-11
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  • Publisher: Elsevier

Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped create this field and are expanding the promise of gene therapy for the future of bas...