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Accurate Quantification of Chromosomal Lesions Via Short Tandem Repeat Analysis Using Minimal Amounts of DNA
Abstract: Background Cytogenetic aberrations such as deletion of chromosome 5q (del(5q)) represent key elements in routine clinical diagnostics of haematological malignancies. Currently established methods such as metaphase cytogenetics, FISH or array-based approaches have limitations due to their dependency on viable cells, high costs or semi-quantitative nature. Importantly, they cannot be used on low abundance DNA. We therefore aimed to establish a robust and quantitative technique that overcomes these shortcomings. Methods For precise determination of del(5q) cell fractions, we developed an inexpensive multiplex-PCR assay requiring only nanograms of DNA that simultaneously measures allel...
Ohio Medicine
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Pierce's Code
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Corpus Juris
None
Adventures of Ook and Gluk: Kung Fu Cavemen from the Future
Tra-la-laaa! Dav Pilkey -- ahem -- we mean, George and Harold, the authors of SUPER DIAPER BABY, are back with their second epic novel! Meet Ook and Gluk, the stars of this sensationally silly graphic novel from the creators of Captain Underpants! It's 500,001 BC, and Ook and Gluk's hometown of Caveland, Ohio, is under attack by an evil corporation from the future. When Ook, Gluk, and their little dinosaur pal Lily are pulled through a time portal to 2222, they discover a future world that's even more devastated than their own. Luckily, they find a friend in Master Wong, a martial arts instructor who trains them in the ways of kung fu. Now all they have to do is travel back in time 502,223 years and save the day!
Directory of Physicians in the United States
Also includes osteopathic physician members of the AMA. Organized geographically, data includes physician name and address, medical school, year of license, primary and secondary practice specialty, type of practice, American Specialty Board certification, and Physician's Recognition Award.
