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Multiple Action-Based Design Approaches to Antibacterials
This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.
Feeling Good Together
We all have people in our lives that we just can't seem to get along with. Whether it's our spouse, co-worker or neighbour, something about the relationship just rubs us up the wrong way, and though our natural instinct is to blame the other person, that can just make things worse. In Feeling Good Together, renowned US psychiatrist Dr David Burns applies his successful method of cognitive interpersonal therapy to teach us how to take control of our relationships. Building on the principles that he first introduced in Feeling Good (over 4 million copies sold), Burns offers innovative techniques designed to improve communication skills and shows us how to cope with different personality types, such as the big ego, the jealous type, the stubborn mule and the critic, and reveals the five secrets of effective communication. This groundbreaking book will identify the behaviours that are sabotaging your relationships and give you the tools to change.
Schizophrenia
Our understanding of schizophrenia has advanced considerably over the last 10 years, particularly with regard to neurobiological and psychological factors. This book brings together disparate literature into an accessible resource.
50 Battles That Changed the World
An informative look at the military conflicts that most altered the course of history and civilization, from ancient times to the modern world. Rather than celebrating warfare, 50 Battles That Changed the World looks at the clashes the author believes have had the most profound impact on world history. Ranked in order of their relevance to the modern world, these struggles range from the ancient past to the present day and span the globe many times over. Some of the battles in this book are familiar to us all—Bunker Hill, which prevented the American Revolution from being stillborn, and Marathon, which kept the world’s first democracy alive. Others may be less familiar—the naval battle at Diu (on the Indian Coast), which led to the ascendancy of Western Civilization and the discovery of America, and Yarmuk, which made possible the spread of Islam from Morocco to the Philippines. With remarkable accounts of both famous and lesser-known clashes, 50 Battles That Changed the World provides impressive insight into the battles that shaped civilization as we know it.
Prediction of Protein Structures, Functions, and Interactions
The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and ...
Hans Jonass Ethic of Responsibility
Articulates the fundamental importance of ontology to Hans Jonass environmental ethics. Despite his tremendous impact on the German Green Party and the influence of his work on contemporary debates about stem cell research in the United States, Hans Jonass (19031993) philosophical contributions have remained partially obscured. In particular, the ontological grounding he gives his ethics, based on a phenomenological engagement with biology to bridge the is-ought gap, has not been fully appreciated. Theresa Morris provides a comprehensive overview and analysis of Jonass philosophy that reveals the thread that runs through all of his thought, including his work on the philosophy of...
Conduct Disorders in Children and Adolescents
Conduct disorder is the most prevalent emotional disorder in children and adolescents, and therefore requires special attention from clinicians. Conduct Disorders in Children and Adolescents is first in providing a comprehensive and balanced view of this field. It addresses the biological, psychological, and interpersonal aspects of aggressive behavior and conduct disorders, and includes the most current clinical research. Conduct Disorders in Children and Adolescents first examines the phenomenology, etiology, and diagnosis of conduct disorders, then describes therapeutic and preventive interventions. It covers the range of treatments now available, including individual, family, group, and behavior therapy; hospitalization; and residential treatment. Special chapters address the new therapeutic interventions of pharmacotherapy and parent management training.
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