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Dear Academicians, Readers and Educators, We are pleased to present the issue of the International Journal of Secondary Metabolite as a special issue entitled ‘I. International Congress on Medicinal and Aromatic Plants - “Natural And Healthy Life”’. This special issue contains some of scientific studies presented in the congress. Hosting the I. International Medical and Aromatic Plant Congress, held in Konya on 9-12 May 2017, by the coorperation T.R. Ministry of Forestry and Water Affairs, General Directorate of Forestry and Necmettin Erbakan University was a great honor for us. The total number of abstract submission for the congress was 1923. After the scientific evaluation, 85 abs...
Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action.
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
Competition is present for almost every sector nowadays. Therefore, it is vital for companies to develop a set of strategies in order to survive in the competitive environment of a globalized world. This book discusses how and why not every strategy is appropriate for every sector. The volume offers a qualified and comprehensive analysis to determine effective competitive strategies taking into account the many different factors that affect company performance.
The Ottoman Empire, together with the Roman Empire and the British Empire, is one of the greatest three world empires. Through its reign of more than 600 years in the most important regions of the world like the Balkan, Middle East and the Caucasus the Ottoman Empire was one of major actors taking part in the formation of the present world. The Ottoman sovereignty lasting for centuries left behind deep traces, which impact is felt even in the present-day world policy. The political and religious policies of the Ottoman Empire played a great role in the formation of the present modern world. The Ottoman Empire with its history lasting for more than 600 years was the last world order, which could not be replaced by a new one up to date.