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Abstract: Interactions of the bacterial lectin LecA with the host cells glycosphingolipid Gb3 have been shown to be crucial for the cellular uptake of the bacterium Pseudomonas aeruginosa. LecA-induced Gb3 clustering, referred to as lipid zipper mechanism, leads to full membrane engulfment of the bacterium. Here, we aim for a nanoscale force characterization of this mechanism using two complementary force probing techniques, atomic force microscopy (AFM) and optical tweezers (OT). The LecA-Gb3 interactions are reconstituted using giant unilamellar vesicles (GUVs), a well-controlled minimal system mimicking the plasma membrane and nanoscale forces between either bacteria (PAO1 wild-type and L...
This volume examines mechanisms for regional peacemaking and conflict management in Europe and the Middle East. To date little research has been devoted to uncovering the conditions for peace, and the factors that contribute to stabilizing the state of peace. This volume assesses the factors that contribute to regional pacification, the incentives that motivate states in establishing peaceful relations, and most importantly, how regions become peaceful. It discusses the conditions under which various types of ‘peace’ might emerge on a regional level and the factors most likely to determine the outcome. The book takes an innovative approach through a systematic comparison of two regions t...
O livro Satisfação dos Stakeholders está dividido em duas partes: A primeira focada em aspectos mais teóricos e acadêmicos abordando taxonomia, gestão, governança, evolução, perspectiva futura e uma apresentação da Mariz SOI de responsabilidade. A segunda parte do livro traz uma abordagem mais pratica em diferentes dimensões como projeto, gestão de pessoas, redes comunicação relacionamentos, implementação e exemplos de modelos. A obra conta com a contribuição de especialistas como: Christina Carvalho Pinto, Daniel Wajcman Magalhães, Frederico Mussi, Gilberto Braga, Gustavo Mançanares Leme, Lia Hasenclever, Luis Sá Lucas e Yuri Oliveira de Lima. O prefácio é assinado por Ed Freeman, R. Ed Freeman Filósofo americano e professor de administração de empresas na Darden School da University of Virginia, particularmente conhecido por seu trabalho sobre a teoria das partes interessadas (Stakeholder Theory).
Revolutionary analysis of the risky role of trust in foreign policy through the assessment of European microstates and their partners
Examining the clandestine and subversive activities of Algerian nationalists in West Germany and Europe, Mathilde Von Bulow sheds new light on the extent to which FLN activities and French counter-measures impacted the conflict in Algeria and the politics of the global Cold War.
International journal for sociology and social psychology.
Investigating the theoretical and empirical relationships between transparency and trust in the context of surveillance, this volume argues that neither transparency nor trust provides a simple and self-evident path for mitigating the negative political and social consequences of state surveillance practices. Dominant in both the scholarly literature and public debate is the conviction that transparency can promote better-informed decisions, provide greater oversight, and restore trust damaged by the secrecy of surveillance. The contributions to this volume challenge this conventional wisdom by considering how relations of trust and policies of transparency are modulated by underlying power ...
This volume examines mechanisms for regional peacemaking and conflict management in Europe and the Middle East. To date little research has been devoted to uncovering the conditions for peace, and the factors that contribute to stabilizing the state of peace. This volume assesses the factors that contribute to regional pacification, the incentives that motivate states in establishing peaceful relations, and most importantly, how regions become peaceful. It discusses the conditions under which various types of ‘peace’ might emerge on a regional level and the factors most likely to determine the outcome. The book takes an innovative approach through a systematic comparison of two regions t...