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"You cannot imagine what it is like in America."
The United States. The land of unimagined opportunities. A place of longing for many Germans for decades. This book describes why people from the Bavarian Forest emigrated to the United States from 1841 to 1931. Diverse documents from German and American archives, historical records, and maps, assembled over many years, are augmented by a wealth of authentic, fascinating letters, photographs, and diary entries from the emigrating families. Vivid conversations and meetings with present-day descendants bring the story full circle! You will experience · the hard life in the Bavarian Forest villages · the hopeful letters from America · the attempts of the authorities to thwart emigration plans · the arduous and often painful preparations for the trip · the adventure-filled, transatlantic crossing 'tween deck · the critical examinations on Ellis Island and · the difficult new beginning in the New World This book forms the basis of the exhibits in the "Born in Schiefweg" Emigration Museum in the Bavarian Forest. It also found its way into the permanent exhibition of the German Emigration Center in Bremerhaven, Germany.
Fluorescence Microscopy
Zu dem Thema gibt es viele Publikationen, die von Experten für Experten geschrieben wurden. Dieses Buch wendet sich insbesondere an Studenten höherer Semester und Forscher, denen das Hintergrundwissen der Physik fehlt, um neuartige Verfahren der Fluoreszenzmikroskopie zu verstehen. Die zweite Auflage wartet mit neuen Kapiteln und einer erweiterten Einführung auf. Der Schwerpunkt liegt auf der hochauflösenden und Einzelmolekül-Mikroskopie. Jedes Kapitel wurde von einem anerkannten Experten des Fachgebiets geschrieben und sorgfältig überarbeitet, um so die Entwicklungen der letzten Jahre wiederzugeben.
Calcium Signaling
Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.
The Gb3-enriched CD59/flotillin Plasma Membrane Domain Regulates Host Cell Invasion by Pseudomonas Aeruginosa
Abstract: The opportunistic pathogen Pseudomonas aeruginosa has gained precedence over the years due to its ability to develop resistance to existing antibiotics, thereby necessitating alternative strategies to understand and combat the bacterium. Our previous work identified the interaction between the bacterial lectin LecA and its host cell glycosphingolipid receptor globotriaosylceramide (Gb3) as a crucial step for the engulfment of P. aeruginosa via the lipid zipper mechanism. In this study, we define the LecA-associated host cell membrane domain by pull-down and mass spectrometry analysis. We unraveled a predilection of LecA for binding to saturated, long fatty acyl chain-containing Gb3...
Josef and Anna Maria (Lenz) Drehobl Family
Josef Drehobl, son of Josef Drehobl and Theres Mandl, was born 24 December 1828 in Kreuzberg, Germany. He married Anna Maria Lenz (1830-1902), daughter of Matthias Lenz and Anna Maria Lang, in 1863. They had twelve children. They emigrated in 1885. He died in 1908 in Chicago, Illinois.
