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Wind Retrofit
This document is a study of the different wind turbine operations and the need for upgrading the old ones. Old wind turbines do not have power electronics, but there is the option to refurbish them and upgrade their technology. Therefore, this upgrade will be studied in terms of economic viability and market opportunity. The idea of doing this project was motivated by the fact that I've been working at Asea Brown Boveri (ABB) since the first of July at the Wind Retrofit department, where a new product is being developed, ABB Wind Retrofit. This product is about refurbishing old wind turbines electrically and feeding them with new power electronics, given that, I thought it could be interesting for me and for the company to study this market opportunity in depth.
Adjuvant Therapy of Breast Cancer
The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloquent rebuttal to those who would argue that we have made no progress in the treatment of cancer. Many of the tumors that we have been most successful in curing with chemotherapy and other newer forms of treatment are relatively uncommon. In contrast, breast cancer continues to be the single most common malignancy among women in the western world, is increasingly a cause of death throughout Asia and Third-World countries, and remains one of the most substantial causes of cancer mortality world wide. The use of mammography as a means of early det...
Print Culture and Peripheries in Early Modern Europe
Despite the fact that, if only by number, small and peripheral cities played an important role in fifteenth and sixteenth-century European print culture, book history has mainly been dominated by monographs on individual big book centres. Through a number of specific case studies, which deploy a variety of methods and a wide range of sources, this volume seeks to enhance our understanding of printing and the book trade in small and peripheral European cities in the fifteenth and sixteenth centuries, and to emphasize the necessity of new research for the study of print culture in such cities.
Nucleic Acids Chemistry
This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
Design and Delivery of SiRNA Therapeutics
This volume details protocols on rationale design of therapeutic siRNA molecules and its encapsulation with smart vehicles to overcome the barriers to an effective administration in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Design and Delivery of SiRNA Therapeutics aims to ensure successful results in the further study of this vital field. This volume details protocols on rationale design of therapeutic ...
Lothagam
Few aspects of American military history have been as vigorously debated as Harry Truman's decision to use atomic bombs against Japan. In this carefully crafted volume, Michael Kort describes the wartime circumstances and thinking that form the context for the decision to use these weapons, surveys the major debates related to that decision, and provides a comprehensive collection of key primary source documents that illuminate the behavior of the United States and Japan during the closing days of World War II. Kort opens with a summary of the debate over Hiroshima as it has evolved since 1945. He then provides a historical overview of thye events in question, beginning with the decision and program to build the atomic bomb. Detailing the sequence of events leading to Japan's surrender, he revisits the decisive battles of the Pacific War and the motivations of American and Japanese leaders. Finally, Kort examines ten key issues in the discussion of Hiroshima and guides readers to relevant primary source documents, scholarly books, and articles.
Chronic Liver Failure
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
The Flight of Icarus
Exploring autobiographical texts written by European urban craftsmen from the 15th to the 18th centuries, this book studies memoirs, diaries, family chronicles, travel narratives, and other forms of personal writings from Spain, France, Italy, Germany, and England. In the process, it reveals the significance of written self-expression in early modern popular culture.
