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Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow
Streptococcus pneumoniae is a major cause of community acquired pneumonia and septicaemia in humans. These diseases are frequently associated with thromboembolic cardiovascular complications. Pneumococci induce the exocytosis of endothelial Weibel-Palade Bodies and thereby actively stimulate the release of von Willebrand factor (VWF), which is an essential glycoprotein of the vascular hemostasis. Both, the pneumococcus induced pulmonary inflammation and the thromboembolytic complications are characterized by a dysbalanced hemostasis including a marked increase in VWF plasma concentrations. Here, we describe for the first time VWF as a novel interaction partner of capsulated and non-encapsula...
Early Nineteenth-century German Settlers in Ohio (mainly Cincinnati and Environs), Kentucky, and Other States
Germany immigration authority, Clifford Neal Smith spent a number of years ferreting out surrogate passenger information from the periodical literature. In one instance, Mr. Smith transcribed the genealogical contents, published between 1869 and 1877, of Volumes 1 through 9 of Der Deutsche Pioniere, a monthly magazine issued by the Deutsche Pioniereverein (Union of German Pioneers) founded in Cincinnati, Ohio. Mr. Smith provides the following particulars on each German-American pioneer found in that periodical: name, place of origin in Germany, town or county of residence, reference to the original source, and biographical data provided in the original notice. While most of the early entries pertain to Germanic inhabitants of Ohio, later issues of Der Deutsche Pioniere refer to deceased persons living in Kentucky and neighboring states.
In the Shadow of Billy the Kid
The events of July 19, 1878, marked the beginning of what became known as the Lincoln County War and catapulted Susan McSween and a young cowboy named Henry McCarty, alias Billy the Kid, into the history books. The so-called war, a fight for control of the mercantile economy of southeastern New Mexico, is one of the most documented conflicts in the history of the American West, but it is an event that up to now has been interpreted through the eyes of men. As a woman in a man’s story, Susan McSween has been all but ignored. This is the first book to place her in a larger context. Clearly, the Lincoln County War was not her finest hour, just her best known. For decades afterward, she ran a successful cattle ranch. She watched New Mexico modernize and become a state. And she lived to tell the tales of the anarchistic territorial period many times.
The Pennsylvania-German Society: 1914
Includes proceedings, addresses and annual reports.
The Descendants of Daniel Lehman
Daniel Lehman was a descendant of Hans Lehman, a Swiss-born immigrant who came to Rapho Township, Lancaster County, Pennsylvania in 1737. Daniel married Anna Huber. Descendants lived in Pennsylvania, Maryland, Virginia, Missouri, Ohio, and elsewhere.
