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Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow
Streptococcus pneumoniae is a major cause of community acquired pneumonia and septicaemia in humans. These diseases are frequently associated with thromboembolic cardiovascular complications. Pneumococci induce the exocytosis of endothelial Weibel-Palade Bodies and thereby actively stimulate the release of von Willebrand factor (VWF), which is an essential glycoprotein of the vascular hemostasis. Both, the pneumococcus induced pulmonary inflammation and the thromboembolytic complications are characterized by a dysbalanced hemostasis including a marked increase in VWF plasma concentrations. Here, we describe for the first time VWF as a novel interaction partner of capsulated and non-encapsula...
Calculus: Single and Multivariable
Calculus: Single and Multivariable, 7th Edition continues the effort to promote courses in which understanding and computation reinforce each other. The 7th Edition reflects the many voices of users at research universities, four-year colleges, community colleges, and secondary schools. This new edition has been streamlined to create a flexible approach to both theory and modeling. The program includes a variety of problems and examples from the physical, health, and biological sciences, engineering and economics; emphasizing the connection between calculus and other fields.
Functions Modeling Change, Textbook and Student Solutions
Prepares readers for the study of calculus, presenting families of functions as models for change. The materials in this book stress conceptual understanding and multiple ways of representing mathematical ideas.
Hughes Hallett Student Solutions Manual to accompany Calculus Combo
This Student Solutions Manual is meant to accompany Calculus: Single and Multivariable, 4th Edition. This book has the ability of striking a balance between concepts, modeling, and skills, this highly acclaimed book arms readers with an accessible introduction to calculus. It builds on the strengths from previous editions, presenting key concepts graphically, numerically, symbolically, and verbally. Guided by this innovative Rule of Four approach, the fourth edition examines new topics while providing readers with a strong conceptual understanding of the material.
Calculus Single and Multivariable
This package includes a copy of ISBN 9780470888612 and a registration code for the WileyPLUS course associated with the text. Before you purchase, check with your instructor or review your course syllabus to ensure that your instructor requires WileyPLUS. For customer technical support, please visit http://www.wileyplus.com/support. WileyPLUS registration cards are only included with new products. Used and rental products may not include WileyPLUS registration cards. This Sixth Edition of Calculus continues the effort to promote courses in which understanding and computation reinforce each other. Calculus: Single and Multivariable 6th Edition reflects the many voices of users at research uni...
Multivariable Calculus
This text is an unbound, binder-ready edition. The fifth edition of Calculus brings together the best of both new and traditional curricula in an effort to meet the needs of even more instructors teaching calculus. The author team's extensive experience teaching from both traditional and innovative books and their expertise in developing innovative problems put them in an unique position to make this new curriculum meaningful to students going into mathematics and those going into the sciences and engineering. Calculus: Single Variable, 5e exhibits the same strengths from earlier editions including the Rule of Four, an emphasis on modeling, exposition that students can read and understand and a flexible approach to technology. The conceptual and modeling problems, praised for their creativity and variety, continue to motivate and challenge students. The fifth edition includes even more problems and additional skill-building exercises.
Functions Modeling Change
This is a new edition of the precalculus text developed by the Consortium based at Harvard University and funded by a National Science Foundation Grant. The text is thought-provoking for well-prepared students while still accessible to students with weaker backgrounds. It provides numerical and graphical approaches as well as algebraic approaches to give students another way of mastering the material. This approach encourages students to persist, thereby lowering failure rates. A large number of real-world examples and problems enable students to create mathematical models that will help them understand the world in which they live. The focus is on those topics that are essential to the study of calculus and these topics are treated in depth. Linear, exponential, power, and periodic functions are introduced before polynomial and rational functions to take advantage of their use to model physical phenomena. Building on the Consortium's Rule of Four: Each function is represented symbolically, numerically, graphically, and verbally where appropriate.
Student Solutions Manual to accompany Calculus: Single Variable
This Student Solutions Manual is meant to accompany, Calculus: Single Variable, 5th Edition, by Deborah Hughes- Hallett. Calculus teachers recognize Calculus as the leading resource among the "reform" projects that employ the rule of four and streamline the curriculum in order to deepen conceptual understanding. The fifth edition uses all strands of the "Rule of Four" - graphical, numeric, symbolic/algebraic, and verbal/applied presentations - to make concepts easier to understand. The book focuses on exploring fundamental ideas rather than comprehensive coverage of multiple similar cases that are not fundamentally unique.
Functions Modeling Change, Textbook and Student Solutions Manual
Prepares readers for the study of calculus, presenting families of functions as models for change. The materials in this work stress conceptual understanding and multiple ways of representing mathematical ideas.
