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This textbook provides a practical guide to the diagnosis, management, and treatment of the principle movement disorders.
Parkinson's is the fastest growing neurological disease in the world today. While it is a multidimensional, complex and hitherto lesser known or understood disease, it's impact is profound and life-changing on those who are affected (patients, caregivers and their families). Although this is a disease primarily of the elderly, more and more studies show a concerning trend towards younger patients (age fifty or less). Unfortunately, this disease could be a growing menace to befall Indian society, as India marches on to become a fully industrialized nation. This concern highlights an urgent need for spread of awareness of what is involved: symptoms, causes, implications, modalities of treatment, and care. This book covers all these topics and more, with the core purpose of driving attention to this disease, written by a highly motivated medical professional.... someone who has witnessed the onset, progression and its care...up, close and personal. Dr. Valsangkar handles the topic with a gentle touch, yet keeping a high degree of professional objectivity. Her's is a message of hope and rationality as a means of fighting this challenging ailment.
This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinson’s disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the modulatory procedures of “asleep”, image-guided deep brain stimulation (DBS) and “awake”, microelectrode-guided DBS. The final chapters focus on closed-loop DBS, drug-delivery, gene therapy, and other emerging neurosurgical therapies, highlighting long-standing experimental strategies that are reaching exciting phases of clinical translation. This volume is a valuable tool for accessing the wide spectrum of concepts that currently define this dynamic field.
Deep Brain Stimulation addresses the practical tips required to program and manage deep brain stimulation devices in the clinic. The number of deep brain stimulation devices worldwide will soon eclipse 200,000 and is an approved surgical treatment for medically refractory neurological movement disorders such as Parkinson disease, tremors, and dystonia. It is, therefore, inevitable that clinicians and nurses will require the necessary tools, and exemplary real-life cases, to manage these complex patients. This book offers a case-based approach to common and uncommon neurologic problems related to deep brain stimulator problems. Each case is a clinical pearl, accompanied by a discussion as well as practical tips to improve patient management.
Non-motor Parkinson's: The Hidden Face, Volume 133, the first part of the latest volume in the International Review of Neurobiology series, is an up-to-date, comprehensive textbook addressing the non-motor aspects of Parkinson's disease, a key unmet need. Chapters in this new release include topics such as The hidden face of Parkinson's, JP and non-motor symptoms, Parkinson's: a complex non-motor disease, Neuropathology of NMS of PD, Neurophysiology and animal models related to NMS in PD, Epidemiology of NMS in PD (cohort studies), Genes and NMS in PD, NMS in genetic forms of PD, and Imaging the NMS in PD. Including practical tips for non-specialists and clinical algorithms, this book contai...