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Biologics to Treat Substance Use Disorders
This book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase and cocaine esterase. In addition, the text covers a wide range of new strategies designed to optimize the development and efficacy of biologics. Unlike any other resource, this book reviews how biologics offer exciting new therapeutic opportunities for various psychiatric conditions. Written by experts in the field, Biologics to Treat Substance Use Disorders is as an authoritative reference for psychiatrists, psychologists, and all other medical professionals working with patients suffering from Substance Use Disorders.
Fundamentals of Internet of Things
The Internet of Things (IoT) networks have revolutionized the world and have innumerable real-time applications on automation. A few examples include driverless cars, remote monitoring of the elderly, remote order of tea or coffee of your choice from a vending machine, and home/industrial automation amongst others. Fundamentals of Internet of Things build the foundations of IoT networks by leveraging the relevant concepts from signal processing, communications, net-works, and machine learning. The book covers two fundamental components of IoT networks, namely, the Internet and Things. In particular, the book focuses on networking concepts, protocols, clustering, data fusion, localization, en...
Drug Delivery to the Brain
The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper ...
Interventions for Addiction
Interventions for Addiction examines a wide range of responses to addictive behaviors, including psychosocial treatments, pharmacological treatments, provision of health care to addicted individuals, prevention, and public policy issues. Its focus is on the practical application of information covered in the two previous volumes of the series, Comprehensive Addictive Behaviors and Disorders. Readers will find information on treatments beyond commonly used methods, including Internet-based and faith-based therapies, and criminal justice interventions. The volume features extensive coverage of pharmacotherapies for each of the major drugs of abuse—including disulfiram, buprenorphine, naltrex...
Bio-Inspired Optimization Techniques in Blockchain Systems
In the dynamic landscape of bioinformatics and blockchain technology, a profound challenge is evident: ensuring secure exchange and analysis of complex biological data while maintaining data integrity and ownership. Traditional methods fall short in seamlessly transferring genomic data, spurring the fusion of blockchain innovation and optimization algorithms as a groundbreaking solution. Biology-Inspired Optimization Techniques in Blockchain Systems directly addresses the data integrity and ownership dilemma in bioinformatics and blockchain. Despite the intricacies of genomic data, blockchain's potential solution faces obstacles like data volume and slow transactions. These challenges are adeptly overcome through optimization algorithms. The book, authored by experts in bioinformatics, blockchain, and optimization, offers a comprehensive guide, showcasing how blockchain architecture and biological data intricacies can harmonize. It provides a blueprint for using blockchain to store genomic variants and aligned reads. This work empowers developers, data scientists, and researchers to overcome technological barriers, redefining the landscape of bioinformatics and beyond.
Privacy-Aware Knowledge Discovery
Covering research at the frontier of this field, Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques presents state-of-the-art privacy-preserving data mining techniques for application domains, such as medicine and social networks, that face the increasing heterogeneity and complexity of new forms of data. Renowned authorities
Algorithmic Aspects of Manipulation and Anonymization in Social Choice and Social Networks
This thesis presents a study of several combinatorial problems related to social choice and social networks. The main concern is their computational complexity, with an emphasis on their parameterized complexity. The goal is to devise efficient algorithms for each of the problems studied here, or to prove that, under widely-accepted assumptions, such algorithms cannot exist. The problems discussed in Chapter 3 and in Chapter 4 are about manipulating a given election, where some relationships between the entities of the election are assumed. This can be seen as if the election occurs on top of an underlying social network, connecting the voters participating in the election or the candidates ...
