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Mitochondrial Dynamics and Neurodegeneration
Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.
Mitochondria: The Anti- cancer Target for the Third Millennium
This book will be focused on mitochondria as very promising targets for anti-cancer drugs, yet to be fully exploited. It will contain chapters focused on aspects of basic research as well as on clinical relevance, which will be written by specialists in the field. That the role of mitochondria in human pathologies goes beyond the neoplastic diseases will be documented by a chapter of the role of mitochondria in Friedreich's ataxia.
L'esclavage, du souvenir à la mémoire
Cet ouvrage propose une étude de grande envergure, première du genre. sur la mémoire et le souvenir de l'esclavage. En analysant les débats politiques et académiques des vingt dernières années, l'auteur dégage deux approches : celle du soupçon politique (victimisation, instrumentalisation, surenchère) et celle du doute anthropologique (fragilité, absence, vide). Ayant établi ce constat, Christine Chivallon part alors à la recherche des traces du souvenir de l'esclavage, ainsi que des témoins qui les transmettent. pour comprendre la teneur des expressions mémorielles issues de l'expérience esclavagiste. L'étude de l'Insurrection du sud, qui a opposé, à la Martinique, ancien...
Complementary Therapies for the Body, Mind and Soul
Complementary Therapies (CT) refers to the practices, products, or health systems that are outside the realm of conventional medicine, used to treat disease or to promote health and well-being. Defining CT is difficult, because the field is very broad and constantly changing. The title of this book includes the words body, mind, and soul. The body and the mind (and their reciprocal relations) have been extensively studied scientifically. What about the soul? The book brings some points about this new ground in CT. We hope you find in the present work the sincere desire to collaborate with the dissemination of knowledge. May this book be useful and pleasant to you.
Mineral and Metal Neurotoxicology
Trace minerals and metals such as zinc, copper, and magnesium are accepted as a "natural" part of the human system. Interactions of some elements and/or disturbances in trace-metal or mineral homeostasis can, however, be toxic to the central nervous system (CNS). Mineral and Metal Neurotoxicology describes a wide range of basic and clinical issues
Plant Metabolomics
Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Ethology and Psychopharmacology
In recent years, valuable new insight has been gained into the often complex effects which drugs have on behaviour. Here, an international group of contributors provide an authoritative and interesting account of contemporary studies in the interdisciplinary arena of ethology and psychopharmacology. They describe up-to-the-minute research in many areas where ethopharmacological analysis has made an enormous impact ? most particularly in the study of anxiety, depression, aggression and defence. This work will be of value to psychologists and psychopharmacologists at research, graduate and senior undergraduate level and to those wishing to evaluate current work in this important field.
Ecometabolomics
Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. - Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites - Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism - Covers both NMR and MS-based approaches
