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The Biology of Glial Cells: Recent Advances
This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.
Trinucleotide Repeat Protocols
Trinucleotide repeats are relatively common in the human genome. These simple repeats have received much attention since epoch-making discoveries were made that particular trinucleotide repeats are expanded in the causal genes of human hereditary neurological disorders. For example, the CGG repeat is expanded in fragile X syndrome at the 5' untranslated region (UTR) of its causal gene. In myotonic dystrophy, it is the CTG repeat that is expanded at the 3' UTR of its causal gene. The CAG repeat was also found expanded in coding regions of the genes responsible for X-linked spinal and bulbar muscular atrophy, Huntington’s disease, spinocerebellar ataxia, and other disorders. On the other han...
Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Fundamentals and Properties of Multifunctional Nanomaterials
Fundamentals and Properties of Multifunctional Nanomaterials outlines the properties of highly intricate nanosystems, including liquid crystalline nanomaterials, magnetic nanosystems, ferroelectrics, nanomultiferroics, plasmonic nanosystems, carbon-based nanomaterials, 1D and 2D nanomaterials, and bio-nanomaterials. This book reveals the electromagnetic interference shielding properties of nanocomposites. The fundamental attributes of the nanosystems leading to the multifunctional applications in diverse areas are further explored throughout this book. This book is a valuable reference source for researchers in materials science and engineering, as well as in related disciplines, such as chemistry and physics. - Explains the concepts and fundamental applications of a variety of multifunctional nanomaterials; - Introduces fundamental principles in the fields of magnetism and multiferroics; - Addresses ferromagnetics, multiferroics, and carbon nanomaterials.
Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System
Proteolysis by the ubiquitin-proteasome pathway (UPP) in the nervous system has been extensively studied both in the context of normal physiological function as well as abnormal pathological conditions. Although ubiquitin was used as a marker of brain pathology, the normal functions of the UPP were not studied much in the nervous system until the 1990s. The early investigations focused on synaptic plasticity which was followed by studies on the roles of protein degradation in the development of the nervous system. Research on the role of abnormal roles of the UPP follows a parallel trajectory. Since the 2000s, the field has grown to encompass many subareas of research and several model syste...
The Indian Nation in 1942
Contributed articles on the Quit India Movement, 1942.
Some Essays on History of Marginal People: Challenges and Changes
This book tries to probe the historical perspectives on various aspects such as marginal people and their various problems, problem of identity or identity crisis, process of social transformation known in history as ‘Sanskritization’ is to ‘associate higher status with higher castes’, the social awakening movement, history of ‘Baul Community' is one of the non-institutional group in our Society, ‘Duars Allowance’, the Indian tribals and their aboriginality and nature, Christian Missionary’s Activities for the Educational Development of Tribal society and so on. Eleven several research papers in this volume is intended to draw the attention of students, academicians to this research on different corners of historical study in Indian perspectives. It can also be read by more discerning general reader interested in probing these topics. The focus of each chapter is on the new trends in research in particular fields. An attempt has been made to introduce the key concepts which have now entered the regional, national, international study in Indian perspectives.
Annual Report of the Registrar of Newspapers for India
Reports for 1958-1970 include catalogues of newspapers published in each state and Union Territory.
