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Neurobiology of Opioids
Dedicated to Professor Albert Herz, a leading investigator in opioid research, this book provides comprehensive information on the biology of exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an in-depth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.
Beat Depression to Stay Healthier and Live Longer
Clinical depression is a serious medical illness that not only can turn a happy retirement into a time of misery, but also leads to a wide range of health problems. Depression increases the rate of disease such as stroke, heart disease, and Alzheimer’s disease and worsens the course of others such as diabetes, chronic lung disease, and cancer. It also contributes to avoidable disability and premature death. Beat Depression to Stay Healthier and Live Longer alerts readers to this untold story. It challenges beliefs that depression is normal in old age because old age is depressing, instead helping readers see that depression is a serious brain disease, often related to changes in the brain ...
Tau Biology
This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.
The Emotional Mind
Tracing the leading role of emotions in the evolution of the mind, a philosopher and a psychologist pair up to reveal how thought and culture owe less to our faculty for reason than to our capacity to feel. Many accounts of the human mind concentrate on the brain’s computational power. Yet, in evolutionary terms, rational cognition emerged only the day before yesterday. For nearly 200 million years before humans developed a capacity to reason, the emotional centers of the brain were hard at work. If we want to properly understand the evolution of the mind, we must explore this more primal capability that we share with other animals: the power to feel. Emotions saturate every thought and pe...
Photoperiodism, Melatonin and the Pineal
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Encyclopedia of Psychopharmacology
Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.
Steroid Hormone-dependent Organization of Neuroendocrine Functions
Patchev, a researcher with a German pharmaceutical company, and Almeida (neuroendocrinology, Max Planck Institute of Psychiatry, Munich) succinctly review the current understanding of steroid hormones and brain organization. They survey the various and often conflicting notions now operating in the field, along with a quick look at their historical development. They also draw the attention of scientists in different specialties to unorthodox views and what they call white spots in neurotropic steroid action that may help understand the role of steroid hormones in the health and pathogenesis of the central nervous system. Annotation copyrighted by Book News, Inc., Portland, OR
