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Annual Reports in Medicinal Chemistry
Praise for the Series:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development."--Enzymologia"This book is strongly recommended for researchers, teachers, students, administrators - in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inlusion in the scientist's personal library."--Journal of Medicinal Chemistry"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry."--Norman Gilman, Hoffmann-La Roche, Inc, in the JOURNAL OF PHARMACEUTICAL SCIENCESAdvances in Medicinal Chemistry continues to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
Mesoplasticity and its Applications
This monograph written by two Chinese scientists of the younger generation opens a window into the world of thoughts on Mechanical Metallurgy in this fascinating area of our world, characterized by age old cultural heritage as weil as by its dynamic evolution into the future. Based on notions and names all so familiar to the western scientist, and regarding the subject from the point of view of the theoretical mechanical engineer (Yang) as weil as that of the materials and manufacturing engineer (Lee), the authors present a synthesis of both approaches and endeavour to guide the reader from basic theory to engineering applications. Between structural defects in the micrometer scale and the m...
Philosophy and Art in Gurdjieff’s Beelzebub
This book demonstrates that the most forceful contribution to George Gurdjieff's world-view is Sufism, understood as the tradition of seeking truth wherever it can be found, especially at the meeting place of the world religions. Gurdjieff's masterpiece, Beelzebub's Tales to His Grandson, is philosophically analyzed in its use of literary devices to jolt the reader into radical transformation.
Contact Mechanics
This volume contains 44 papers presented at the Third Contact Mechanics International Symposium (CMIS 2001) held in Praia da Consola9ao, Peniche (portugal), June 17-21,2001. This Symposium was the direct continuation of the first two CMIS held in Lausanne (1992) and in Carry-Le-Rouet (1994). Other related meetings, in what concerns scientific topics and participants, took place in the nineties at La Grande Motte (1990), Vadstena (1996), Ferrara (1997), Munich (1998) and Grenoble (1999). The Symposium aimed at gathering researchers with interests in a wide range of topics in theoretical, computational and experimental contact mechanics. The call for papers mentioned topics in tribology, mathe...
Profiles of Drug Substances, Excipients and Related Methodology
Profiles of Drug Substances, Excipients and Related Methodology
Progress in Medicinal Chemistry
Progress in Medicinal Chemistry
IUTAM Symposium on Discretization Methods for Evolving Discontinuities
In recent years, discretization methods have been proposed which are more flexible and which have the potential of capturing (moving) discontinuities in a robust and efficient manner. This monograph assembles contributions of leading experts with the most recent developments in this rapidly evolving field. It provides the most comprehensive coverage of state-of-the art numerical methods for treating discontinuities in mechanics.
Guidelines for Applying Cohesive Models to the Damage Behaviour of Engineering Materials and Structures
This brief provides guidance for the application of cohesive models to determine damage and fracture in materials and structural components. This can be done for configurations with or without a pre-existing crack. Although the brief addresses structural behaviour, the methods described herein may also be applied to any deformation induced material damage and failure, e.g. those occurring during manufacturing processes. The methods described are applicable to the behaviour of ductile metallic materials and structural components made thereof. Hints are also given for applying the cohesive model to other materials.
Reflex Control of the Circulation
Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.
Pulmonary Circulation in Health and Disease
This volume documents the proceedings of a symposium on "The Pulmonary Circulation" held at the Ettore Majorana Center for Scientific Culture, in Erice, Sicily, between 16th July and 21st July 1979. This was attended by about 200 participants drawn from Europe as a whole, but the majority were from Southern Europe. The discussion was recorded either in English or Italian and the tapes were reduced to a verbatim typescript by the Ente Nazionale Interpeti Congresso. The verbatim typescript has been edited using a few guiding principles as foliows: Titles and honorifics have been eliminated unless the 1. statement is addressed to a specific person. The style of the speakers in the discussion ha...
