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The Role of Agreement in Non-finite Predication
This comparative syntactic study claims that agreement is the most central functional category responsible for licensing predication in finite, non-finite and small clauses alike. Intriguing syntactic phenomena like Icelandic infinitival predicates taking non-nominative (quirky) subjects; "psych-impersonal" and "modal" predicates in Italian, Hungarian and Russian; meteorological predicates, existential clauses, post-verbal and null subjects in the so-called" null-subject" VSO languages can all be better analyzed through a concept of predication that is closely related to AGRP, manifesting subject-verb agreement. The overt agreement marking in Hungarian and Portuguese infinitival clauses further strengthens this view. "Obviation" and "control "subjunctive clauses in the Balkan languages, Welsh finite and non-finite infinitival clauses as well as case-marked secondary predicates in Icelandic, Slovak, Hungarian, Russian and Finnish also lend support to an analysis where the []pred] feature is checked in AGRP.
Immunogenomics and Human Disease
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
SuperMEN1
The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulat...
Practical Clinical Endocrinology
This practical book aims to cover the whole scope of clinical endocrinology, including both common and selected rare but important diseases, with an emphasis on practical clinical management. A number of different questions and problems in clinical routine are discussed in this book in an unconventional format. Each topic begins with the presentation of a typical clinical case, and then the topic is approached in a question and answer format linked to the clinical case presented, highlighting the most important questions in diagnosis, differential diagnosis and therapy. Numerous figures and tables are included to help understanding. The book is chiefly intended for doctors in training (preparing for boarding exam in endocrinology or internal medicine), but also for established clinicians who want to broaden or refresh their skills. University students of medicine can also find this book interesting.
Recent Progresses of Non-Coding RNAs in Biological and Medical Research, 2nd Edition
Publisher’s note: In this 2nd edition, the following article has been updated: Xun Y, Tang Y, Hu L, Xiao H, Long S, Gong M, Wei C, Wei K and Xiang S (2019) Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation. Front. Genet. 10:778. doi: 10.3389/fgene.2019.00778
Serum Metabolites in Diagnostics and Therapeutics
Metabolomics can critically assess key metabolic pathways and thus provide data for nutritional deficiencies, metabolic imbalance, environmental burden, and the gut microbiome. Since the metabolite functions are not determined by epigenetic regulation or post-translational modification, quantification and evaluation of metabolites is an highly effective method to capture time-dependent fluctuations and cellular metabolic state, even prior to disease onset. Blood serum is a primary carrier of small molecules in the body, present in the blood of every tissue and organ in the body. It plays a critical role in transporting dissolved gases, nutrients, hormones and metabolic wastes, as well as in the regulation of the pH and ion composition of interstitial fluids, the restriction of fluid losses at injury sites and the defence against toxins and pathogens.
AACR 2022 Proceedings: Part B April 11-13
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
