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Written by a recognized expert in the field, this accessible book acquaints the lay reader with the main features of hormonal diseases, their diagnosis and treatment. From gigantism and dwarfism to polycystic ovary syndrome, overactive thyroid and many more; it also explains what specialists in endocrinology do - and why - when diagnosing and treating patients. Each chapter gives a short introduction to the relevant hormonal disease, with information about the symptoms, diagnosis and treatment presented in an easily comprehensible question and answer format. Simple but accurate diagrams are used to visualize the information. The book clarifies important issues and helps patients to make informed decisions. Last but not least, it includes some current hot topics in endocrine practice as well as fascinating historical facts. It is a must-read for everyone interested in the fascinating world of hormones and their disorders.
This comparative syntactic study claims that agreement is the most central functional category responsible for licensing predication in finite, non-finite and small clauses alike. Intriguing syntactic phenomena like Icelandic infinitival predicates taking non-nominative (quirky) subjects; "psych-impersonal" and "modal" predicates in Italian, Hungarian and Russian; meteorological predicates, existential clauses, post-verbal and null subjects in the so-called" null-subject" VSO languages can all be better analyzed through a concept of predication that is closely related to AGRP, manifesting subject-verb agreement. The overt agreement marking in Hungarian and Portuguese infinitival clauses further strengthens this view. "Obviation" and "control "subjunctive clauses in the Balkan languages, Welsh finite and non-finite infinitival clauses as well as case-marked secondary predicates in Icelandic, Slovak, Hungarian, Russian and Finnish also lend support to an analysis where the []pred] feature is checked in AGRP.
The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulat...
This practical book aims to cover the whole scope of clinical endocrinology, including both common and selected rare but important diseases, with an emphasis on practical clinical management. A number of different questions and problems in clinical routine are discussed in this book in an unconventional format. Each topic begins with the presentation of a typical clinical case, and then the topic is approached in a question and answer format linked to the clinical case presented, highlighting the most important questions in diagnosis, differential diagnosis and therapy. Numerous figures and tables are included to help understanding. The book is chiefly intended for doctors in training (preparing for boarding exam in endocrinology or internal medicine), but also for established clinicians who want to broaden or refresh their skills. University students of medicine can also find this book interesting.
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
Publisher’s note: In this 2nd edition, the following article has been updated: Xun Y, Tang Y, Hu L, Xiao H, Long S, Gong M, Wei C, Wei K and Xiang S (2019) Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation. Front. Genet. 10:778. doi: 10.3389/fgene.2019.00778