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Biosimulation in Drug Development
  • Language: en
  • Pages: 540

Biosimulation in Drug Development

This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms. Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions. Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference.

Digital Teleretinal Screening
  • Language: en
  • Pages: 233

Digital Teleretinal Screening

Digital retinal imaging performed by primary care providers and nurses, followed by remote image interpretation (teleretinal imaging), is rapidly acquiring a crucial role in many parts of the world as it permits the detection of major diseases, such as diabetic retinopathy and glaucoma, in patients who would otherwise be beyond the reach of a trained ophthalmologist. In this book, experts from around the world describe how digital teleretinal screening can be set up and optimally utilized. Technical issues are discussed, and the appropriate use of screening for different diseases and in different age groups is explained. The major part of the book draws upon the clinical experience of leading practitioners in a wide range of teleretinal applications. The result is a comprehensive source of high-quality information for clinicians and other health professionals who are involved in eye care delivery, so that they can assess how teleretinal screening might be applied to their working practice.

Unveiling Machine Learning: Theory, Algorithms and Practical Applications
  • Language: en
  • Pages: 221

Unveiling Machine Learning: Theory, Algorithms and Practical Applications

Dr.Padmaja Pulicherla, Professor, Department of Computer Science and Engineering, Hyderabad Institute of Technology and Management, Affiliated to JNTU, Hyderabad, Telangana, India. Dr.Kasarla Satish Reddy, Professor, Department of Electronics and Communication Engineering, Hyderabad Institute of Technology and Management, Affiliated to JNTU, Hyderabad, Telangana, India. D.Satyanarayana, Assistant Professor, Department of Computer Science and Engineering(DS), Santhiram Engineering College(Autonomous), Nandyal, Andhra Pradesh, India. Dr.R.Sudheer Babu, Associate Professor, Department of Electronics and Communication Engineering, G.Pulla Reddy Engineering College (Autonomous), Kurnool, Andhra Pradesh, India. Dr.Ravi Babu Devareddi, Assistant Professor, Department of Computer Science and Engineering, SRKR Engineering College, Bhimavaram, Andhra Pradesh, India.

Biofertilizers for Sustainable Agriculture and Environment
  • Language: en
  • Pages: 544

Biofertilizers for Sustainable Agriculture and Environment

  • Type: Book
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  • Published: 2019-08-09
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  • Publisher: Springer

This book provides a comprehensive overview of the benefits of biofertilizers as an alternative to chemical fertilizers and pesticides. Agricultural production has increased massively over the last century due to increased use of chemical fertilizers and pesticides, but these gains have come at a price. The chemicals are not only expensive; they also reduce microbial activity in agricultural soils and accumulate in the food chain, with potentially harmful effects for humans. Accordingly, it is high time to explore alternatives and to find solutions to overcome our increasing dependence on these chemicals. Biofertilizers, which consist of plant remains, organic matter and microorganisms, migh...

Genetics, Genomics and Breeding of Sorghum
  • Language: en
  • Pages: 368

Genetics, Genomics and Breeding of Sorghum

  • Type: Book
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  • Published: 2014-07-08
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  • Publisher: CRC Press

Sorghum is one of the hardiest crop plants in modern agriculture and also one of the most versatile. Its seeds provide calorie for food and feed, stalks for building and industrial materials and its juice for syrup. This book provides an in-depth review of the cutting-edge knowledge in sorghum genetics and its applications in sorghum breeding. Each chapter is authored by specialists in their fields to report the latest trends and findings. The book showcases the definitive value of sorghum as a model system to study the genetic basis of crop productivity and stress tolerance and will provide a foundation for future studies in sorghum genetics, genomics, and breeding.

The Chemistry of 1,2,3-Thiadiazoles, Volume 62
  • Language: en
  • Pages: 277

The Chemistry of 1,2,3-Thiadiazoles, Volume 62

1,2,3-Thiadiazoles are a group of heterocycles whose derivatives are important in industry, medicine, and agriculture. This volume provides a complete treatment of this group of heterocycles with an emphasis on syntheses, structural data, properties, reactions, and applications.

Handbook of Antioxidants
  • Language: en
  • Pages: 740

Handbook of Antioxidants

  • Type: Book
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  • Published: 2001-10-26
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  • Publisher: CRC Press

Contains new and expanded material on antioxidants in beverages and herbal products, nitric oxide and selenium, and the effect of vitamin C on cardiovascular disease and of lipoic acid on aging, hyperglycemia, and insulin resistance! Offering over 4200 contemporary references-2000 more than the previous edition-the Second Edition of the Handbook of Antioxidants is an up-to-the-minute source for nutritionists and dietitians, cell biologists and biochemists, cardiologists, oncologists, dermatologists, and medical students in these disciplines.

Reasserting the Rural Development Agenda
  • Language: en
  • Pages: 436

Reasserting the Rural Development Agenda

Presents a reinvigorated agenda on agricultural and rural development in Asia both for research and policy discussions in the coming decades.

MATHEMATICAL MODELLING OF SYSTEMS AND ANALYSIS
  • Language: en
  • Pages: 264

MATHEMATICAL MODELLING OF SYSTEMS AND ANALYSIS

This book is written with the ideology of providing a simple yet concise explanation on the art of developing mathematical models. This lively and engaging text explicates the basics of mathematical modelling, with special focus on its applications and analysis. Organised in thirteen chapters, the book emphasises the theory and classification of systems, modelling using ordinary differential equations, calculus of variations, stability analysis, system identification and parameter estimation techniques. Also, it includes examples from the areas of mechanics, chemical reactions, biology, population dynamics, epidemiology, and other allied fields of science, engineering and technology. This bo...