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Mitochondrial Signaling in Health and Disease
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis. With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate ce...
Research in Computational Molecular Biology
This book constitutes the refereed proceedings of the 11th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2007, held in Oakland, CA, USA in April 2007. The 37 revised full papers address all current issues in algorithmic, theoretical, and experimental bioinformatics.
Pattern Recognition in Bioinformatics
This book constitutes the refereed proceedings of the 6th International Conference on Pattern Recognition in Bioinformatics, PRIB 2011, held in Delft, The Netherlands, in November 2011. The 29 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers cover the wide range of possible applications of bioinformatics in pattern recognition: novel algorithms to handle traditional pattern recognition problems such as (bi)clustering, classification and feature selection; applications of (novel) pattern recognition techniques to infer and analyze biological networks and studies on specific problems such as biological image analysis and the relation between sequence and structure. They are organized in the following topical sections: clustering, biomarker selection and classification, network inference and analysis, image analysis, and sequence, structure, and interactions.
The Assumptions Behind the Theory of Evolution
The theory of evolution is based solidly upon certain assumptions. This would not be a problem if it wasn't for the fact that most of these assumptions are not warranted by the facts of nature, and therefore have not (and can not ever) be codified as facts of nature. Today these unwarranted, and therefore illegitimate assumptions, have found their way into populating not only our textbooks, but also mainstream America, as confirmed facts of nature, when they are not. This book exposes numerous unwarranted and illegitimate evolutionary assumptions pushed upon the unsuspecting public as codified facts of science when they are not codified facts of nature. According to Dr. Jerry Bergman, this is an "excellent book...it promises to be a very important book in this area (referring to the creation/evolution controversy."
التطور الموجه بين العلم والدين
مرة أخرى -لن تكون الأخيرة- مع ملف الداروينية، ومع فرع هو الأكثر خطورة في هذا الملف حيث يلتقي التطور فيه مع العلم والدين. وهذا الكتاب هو في بيان ضعف وتهافت الداروينية من منظور علمي، وأن الدعم المؤسسي والأكاديمي المقدم لها يتجاوز مجرد التأييد العلمي الطبيعي لنظرية تخطئ وتصيب، بل هو غارق حتى الآذان في الأدلجة والتحيز، فضلاً عن التضليل والتدليس المتعمد. وليس في هذا انتقاصٌ للعلم الحديث ...
Primary Cilia
In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella. - Covers protocols for primary cilia across several systems and species - Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time - Relevant to clinicians and scientists working in a wide range of fields
Modified Nucleic Acids
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
