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Bacterial Genomes and Infectious Diseases
The first bacterial genome, Haemophilus influenzae, was completely sequenced, annotated, and published in 1995. Today, more than 200 prokaryotic (archaeal and bacterial) genomes have been completed and over 500 prokaryotic genomes are in va- ous stages of completion. Seventeen eukaryotic genomes plus four eukaryotic chro- somes have been completed. The concept of achieving better understanding of an organism through knowledge of the complete genomic sequence was first demonstrated in 1978 when the first bacteriophage genome, X174, was sequenced. Complete genomic sequences of prokaryotes have led to a better understanding of the biology and evolution of the microbes, and, for pathogens, facil...
The Coming Collapse Of China
Fully revised and updated edition covering China's new membership of the WTO and with a new introduction. 'Damning data and persuasive arguments that should set some Communist knees a-knocking.' Kirkus Reviews'A compelling account of the rot in China's institutions and the forces at work to end the Communist Party's monopoly on power.' James A. Dorn, Cato Institute, Washington D. C., Co-Editor of China's future: Constructive Partner or Emerging Threat? 'Quite simply the best book I know about China's future. Gordon Chang writes marvellously and knows China well. I hope everyone concerned with that country will pay careful consideration to what he sees ahead.' Arthur Waldron, Director of Asian Studies, American Enterprise Institute; Lauder Professor of International Relations, University of Pennsylvania.'A tour de force not to be missed.' Willy Wo-Lap, Senior China Analyst at CNN's Hong Kong office and author of The Era of Jiang Zemin.'When he warns that China's two centuries of troubles are still not over, we had better take notice.' Andrew J. Nathan, Professor of Political Science, Columbia University; Co-Editor, The Tiananmen Papers.
Medical Imaging Informatics
Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows natural healthcare processes, illustrating the roles of data collection and standardization, context extraction and modeling, and medical decision making tools and applications. Medical Imaging Informatics identifies core concepts within the field, explores research challenges that drive development, and includes current state-of-the-art methods and strategies.
The Handbook of Culture and Psychology
This book describes the continued evolution and advancement of cultural and cross-cultural psychology. Renowned authors review the state-of-the-art in well-studied areas such as development, cognition, emotion, personality, psychopathology, psychotherapy, and acculturation, as well as emerging areas such as multicultural identities, cultural neuroscience, and religion. The book is a must read for all culturally informed scholars.
PARP Inhibitors for Cancer Therapy
PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The “synthetic lethality” of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.
Language, Society and Power
This book examines the ways in which language functions, how it influences thought and how it varies according to age, ethnicity, class and gender. It seeks to answer such questions as: How can a language reflect the status of children and older people? Do men and women talk differently? How can our use of language mark our ethnic identity? It also looks at language use in politics and the media and investigates how language affects and constructs our identities, exploring notions of correctness and attitudes towards language use. While it can be used as a stand-alone text, this edition of Language, Society and Power has also been fully cross-referenced with the new companion title: The Language, Society and Power Reader. Together these books provide the complete resource for students of English language and linguistics, media, communication, cultural studies, sociology and psychology. --Book Jacket.
Merchant Vessels of the United States
From 1894/95-1935/36, pt.6 of each volume is issued separately, with titles, 1894/95-1902/03: Code list of merchant vessels of the United States; 1903/04-1935/36: Seagoing vessels of the United States.
