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Arteriovenous malformations (AVM) and arteriovenous fistulas (AVF) differ from all other pathology affecting the central nervous system by their high-flow arteriovenous shunts. Permanent occlusion of these shunts is the essence and the challenge of therapy. Endovascular therapy and radiosurgery became accepted alternatives or adjuncts to surgery. In many instances the choice of the primary therapeutic modality is not clear and arguments can be found for several options. However, microsurgery, endovascular therapy and radiosurgery differ very much with regard to invasiveness, length of stay at the hospital but also residual risk after therapy. The emerging treatment concepts are the object of this book. The result is a unique structured presentation of AVM and AVF therapy.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incomplet...
Washington D. C. , and at the Columbia University New York. In 1967 and 1968 he worked as a gen eral surgeon at the 1st Surgical Department of the Vienna Medical School with Professor Fuchsig. At the Max-Planck Institute in Munich he worked in the years 1968 to 1969 as a neuropathologist. In the year 1969 till 1972 back at the Department of Neurosurgery in Vienna he served as a general neurosurgeon and one of his main goals was pediatric neurosurgery. In Au gust 1972 he moved to Kiel to work with Professor Jensen at the Neurosurgical University Hospital. He had to graduate one more time in Germany and he did this with "Ultrasound Tomography in Neurosurgery". Together with the Department of P...
This volume is a compilation of papers presented at the Tenth International Symposium on Brain Edema held on October 20-23, 1996, in San Diego, California. This follows the sequence of meetings that was initiated 31 years ago in the First International Symposium held in Vienna. Subsequent symposiums were held in Mainz, Montreal, Berlin, Groningen, Tokyo, Baltimore, Bern, and Tokyo CY okohama). A considerable number of papers was chosen from over 100 papers that were received. The organizers wish to thank the Advisory Committee for the excellent work done in selection of the papers. We also wish to thank all the persons who contributed to the success of the Tenth International Symposium, espe...
Stroke is a major cause of death and disability in the U.S. and worldwide. A variety of pathophysiologic episodes or cellular medications occur following a stroke, and knowledge of these aftermath events can lead to potential therapeutic strategies that may reverse or attenuate stroke injury. Cellular events that occur following stroke include the excessive releases of excitatory amino acids, alterations in the genomic responses, mitochondrial injury producing reactive oxygen and nitrogen species (ROS), and secondary injury, often in the setting of reperfusion.
This book stems from the urgent necessity to address neurodegenerative diseases, which are among the most severe health challenges currently confronting society. Neurodegenerative diseases have become a major threat to public health in recent years, impacting millions of people globally and creating a substantial strain on healthcare systems and society as a whole. Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis are examples of these diseases. This book offers a thorough survey of the latest developments in this rapidly growing field. This book is targeted towards a wide range of readers, including academics, researchers, medical professionals, students, policy makers, and anybody else who is interested in the convergence of neuroscience, nanotechnology, and healthcare. Irrespective of one's familiarity with the subject, this book provides motivation and insightful information to bolster our group's endeavors in combating these debilitating diseases.
Rainer Werner Fassbinder is one of the most prominent and important authors of post-war European cinema. Thomas Elsaesser is the first to write a thoroughly analytical study of his work. He stresses the importance of a closer understanding of Fassbinder's career through a re-reading of his films as textual entities. Approaching the work from different thematic and analytical perspectives, Elsaesser offers both an overview and a number of detailed readings of crucial films, while also providing a European context for Fassbinder's own coming to terms with fascism.
This book will discuss and cover standard treatments and advances in some of the most controversial topics in cerebrovascular surgery traversing the whole arena, including open and interventional surgeries. They will be discussed with case scenarios, bail out strategies and complication handling, followed by advances in the subject. Some of the best academic cereberovascular physician will author these chapters with their vast experience. The book will be of particular benefit to neurosurgeons, neurologists, and radiologists. It will be particularly targeting residents, young and experienced faculty in the subject, and will provide first hand up to the mark information and experiences in cerebrovascular surgery.
This book highlights the latest developments in acute and delayed neurovascular injury studies including delayed cerebral vasospasm, early brain injury, micro-circulation compromise, spreading cortical depolarization, neuroinflammation, and long-term cognitive dysfunctions after subarachnoid hemorrhage. About 32 chapters cover original presentations from the 14th international conference on neurovascular events after subarachnoid hemorrhage, held in Los Angeles in October 2017. Neurosurgeons, neurologists, and neuro-ICU practitioners discuss clinical observations, new pilot treatments, clinical trials, academic and industrial interactions, including surgical and endovascular approaches, brain injury monitoring, new developments in brain imaging, ICU management, early brain injury scales and management, counter cortical depolarization management and anti-inflammation management. In addition, animal models used to study acute and delayed neurovascular events, the basic mechanisms of vascular, neuronal, and CSF physiology, new experimental treatment strategies, new frontiers in the treatment of neurovascular injuries, and new research directions are discussed.
This dedicated volume in the series Advances and Technical Standards in Neurosurgery (ATSN) provides a comprehensive approach to diseases of the craniovertebral junction (CVJ) and their management based on the multidisciplinary cooperation of neurosurgeons, anatomists, neuroradiologists, and neuroanesthesiologists. The contributing authors represent the most renowned clinical and surgical experts from Europe and beyond. The main topics highlighted are embryology, normal and abnormal development of the CVJ, including the related vessels, modern radiological contributions to diagnosis, genetic and metabolic factors which may impact on the surgical strategies, the opportunities offered by traditional operative techniques, and the recently introduced minimally invasive and endoscopic surgical modalities. Special emphasis is also placed on the evolution of the principles of surgical treatment as matured during the past decade by experiences in the still open field of pediatric neurosurgery.