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Introduction to Systems Biology
This book is an introduction to the language of systems biology, which is spoken among many disciplines, from biology to engineering. Authors Thomas Sauter and Marco Albrecht draw on a multidisciplinary background and evidence-based learning to facilitate the understanding of biochemical networks, metabolic modeling and system dynamics. Their pedagogic approach briefly highlights core ideas of concepts in a broader interdisciplinary framework to guide a more effective deep dive thereafter. The learning journey starts with the purity of mathematical concepts, reveals its power to connect biological entities in structure and time, and finally introduces physics concepts to tightly align abstra...
Textbook of Diabetes
Over three editions the Textbook of Diabetes has built a reputation as a book that is extremely well-organized and easy to navigate, with exceptional illustrations and an excellent blend of clinical and scientific content. Previously edited by John Pickup and Gareth Williams this fourth edition has four brand new editors from across the globe. The editors have assembled an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The new Textbook of Diabetes has been restructured into 12 parts in one accessible volume and is designed with the busy diabetes care team in mind....
Drug Benefits and Risks
This updated and revised 2nd edition of Drug Benefits and Risks is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs, but in this context also highlighting the social impact which drugs have in modern societies. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases; the book gives guidance on how doctors should act so that drugs can be used effectively and safely; and it encourages the rational use of drugs in society. This publication brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.
The Concept of Community from a Global Perspective
This volume presents essays analysing the ambivalent history of the globally influential political and social concept of community and the paradigms it has engendered in academia and politics. While the term ‘community’ often evokes positive sentiments, it is also linked to oppressive regimes and exclusion. A survey of the term’s use is followed by studies of the sociologist Ferdinand Tönnies and of the use of the term in disciplines such as politics, applied linguistics, anthropology, literary theory, philosophy, and intellectual history. The volume concludes with an analysis of the application of the concept in politics in the UK, debates between liberals and communitarianists, utopianism, and African philosophy. Contributors are: Niall Bond, Christopher Adair-Toteff, Daniel Alvaro, Alexander Wierzock, Sebastian Klauke, Antonin Cohen, Jan Buts, Stéphane Vibert, Rémi Astruc, Elisabeth Bouzonviller, Françoise Orazi, Andrew Vincent, Astrid von Busekist, Robert Kramm, and Thaddeus Metz.
Mann's Pharmacovigilance
Highly Commended at the BMA Medical Book Awards 2015 Mann’s Pharmacovigilance is the definitive reference for the science of detection, assessment, understanding and prevention of the adverse effects of medicines, including vaccines and biologics. Pharmacovigilance is increasingly important in improving drug safety for patients and reducing risk within the practice of pharmaceutical medicine. This new third edition covers the regulatory basis and the practice of pharmacovigilance and spontaneous adverse event reporting throughout the world. It examines signal detection and analysis, including the use of population-based databases and pharmacoepidemiological methodologies to proactively mon...
The Law of Off-label Uses of Medicines
This book examines the regulatory framework for untested and unapproved uses (off-label uses) of medicines in the EU, UK, and USA. Before reaching patients, medicines are extensively tested by manufacturers and approved by regulators to minimise the risk of adverse reactions. However, physicians can prescribe pharmaceuticals for off-label uses, widespread in paediatrics, oncology, rare diseases and, more recently, in treatment for Covid-19. While off-label uses may offer hope, they may also expose patients to risks and uncertainties. Clarification is therefore needed to improve the protection of patients' rights while enhancing legal certainty for health actors. To this end, this work clarif...
Evidence-Based Medical Monitoring
Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising. This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.
Mathematics for Human Flourishing in the Time of COVID-19 and Post COVID-19
The International Chair in Mathematical Physics and Applications (ICMPA - UNESCO chair), University of Abomey-Calavi, Benin, and the Center for Applied Mathematics of the Faculty of Mechanical Engineering Niš, CAM-FMEN, organized a webinar on Mathematics for human flourishing in the time of COVID-19 and post COVID-19, 21 October 2020, supported by the City of Niš. The objectives of the webinar were to give precise information about the work that scientists do to cure the disease, to push forward technology, to understand our society and create new expressions of humanity, and to question the role of mathematics in the responses to this pandemic.
Postcollectivity
Most of the phenomena described in this book have arisen as a result of various crises, disasters, threats, and forms of violence (such as wars, refugee crises, and political regimes, but also devastating practices of the anthropogenic drive and environmental pollution). Others are a form of response to new political, social and cultural changes that we are experiencing due to the rapid development of technology or progressive economic stratification. The research perspective proposed in Postcollectivity draws on the authors' approaches, combining academic and theoretical discourse with social engagement and artistic practice with critical thought. Contributors are: Harshavardhan Bhat, Stephen Dersley, Adela Goldbard, Carly E. Gray, Agnieszka Jelewska, Peter H. Kahn, Jr., Michał Krawczak, Grant Leuning, Ania Malinowska, Anna Nacher, Andrzej W. Nowak, Julian Reid, Pepe Rojo, Sarena Sabine, Jens Schröter, Jan Stasieńko and Brett Zehner.
It All Depends on the Dose
This is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physician Paracelsus, to the present, when poisons are actively being turned into beneficial medicines. Chapter 5 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.
