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Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, thi...
This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
A 66-day plan for going sugar-free from an eating disorder specialist and therapist who broke free of her own sugar addiction. Our relationship with food can be complicated: for many, food soothes painful emotions, it nurtures, it numbs, it provides a 'high'. Breaking Up With Sugar offers a plan for the complete transformation of many people's destructive relationship with food. For these people, sugar is often the culprit: it produces physical, neurological and endocrine changes that render the individual powerless over their compulsion to eat. Molly Carmel struggled with her own eating disorder for over 20 years and finding no solutions in available treatments, she created The Beacon, where she helps clients recover from similar addictions. Her step-by-step instructions are designed to take the guesswork out of sugar-free eating and help people start a new, healthier relationship with food. With 8 vows to return to and rely on, and guidance on how to divorce dieting forever, Breaking Up With Sugar offers an individualised, sustainable and realistic plan for eating and thriving for life.
Set your Mediterranean table for two with perfectly portioned dishes With crisp veggies, succulent seafood, hearty grains, and healthy oils, the Mediterranean diet makes nutritious eating a pleasure. This cookbook brings its bright flavors and bountiful health benefits to your table with recipes designed for two people. Relax and savor a delicious breezy seaside breakfast or a simple rustic dinner, all without leaving home. Together, discover how a Mediterranean lifestyle can reduce the risk of heart disease, aid in weight loss, and more. Change your life with healthy eating by cooking up meals that feature quick prep times and seasonal, accessible ingredients like the below: CITRUS FENNEL S...
It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; howev...